Bis(7)-tacrine
TL;DR: Bis(7)-tacrine (CAS 224445-12-9) is a chemical compound with molecular formula C33H40N4 and molecular weight 492.33 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N,N'-bis(1,2,3,4-tetrahydroacridin-9-yl)heptane-1,7-diamine
Also Known As: bis(7)-Tacrine, Bistacrine, bis(7)-cognitin, Bis-7-Tacrine, 2ckm
| Molecular Formula | C33H40N4 |
|---|---|
| Molecular Weight | 492.33 g/mol |
| LogP | 8.0151 |
| Topological Polar Surface Area | 49.84 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 10 |
| Exact Mass | 492.3253 |
| Heavy Atoms | 37 |
| Complexity | 1270.8795 |
Chemical Identifiers
| CAS Number | 224445-12-9 |
|---|---|
| SMILES | C1CCC2=NC3=CC=CC=C3C(=C2C1)NCCCCCCCNC4=C5CCCCC5=NC6=CC=CC=C64 |
Product Overview
Bis(7)-tacrine (CAS 224445-12-9), with molecular formula C33H40N4 and molecular weight 492.33 g/mol. IUPAC: N,N'-bis(1,2,3,4-tetrahydroacridin-9-yl)heptane-1,7-diamine.
Chemical Property Profile of Bis(7)-tacrine
Property Insights of Bis(7)-tacrine
The XLogP value of 8.0151 indicates that Bis(7)-tacrine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.84 Ų, Bis(7)-tacrine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bis(7)-tacrine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bis(7)-tacrine?
The CAS number of Bis(7)-tacrine is 224445-12-9.
What is the molecular formula of Bis(7)-tacrine?
The molecular formula of Bis(7)-tacrine is C33H40N4.
What is the molecular weight of Bis(7)-tacrine?
The molecular weight of Bis(7)-tacrine is 492.33 g/mol.
Where can I buy Bis(7)-tacrine?
You can request a quote for Bis(7)-tacrine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bis(7)-tacrine?
Yes, KEHONG BIO provides custom synthesis services for Bis(7)-tacrine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.