Corey-hopkins reagent structure

Corey-hopkins reagent

TL;DR: Corey-hopkins reagent (CAS 22429-12-5) is a chemical compound with molecular formula C10H15N2P and molecular weight 194.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1,3-dimethyl-2-phenyl-1,3,2-diazaphospholidine

Also Known As: 1,3-Dimethyl-2-phenyl-1,3,2-diazaphospholidine, Corey-hopkins reagent, CN1CCN(C)P1c2ccccc2, 2-phenyl-1,3-dimethyl-1,3-diaza-phospholidine, 1,3-Dimethyl-2-phenyl-[1,3,2]diazaphospholidine

CAS: 22429-12-5
Molecular Formula C10H15N2P
Molecular Weight 194.10 g/mol
LogP 1.7
Topological Polar Surface Area 6.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 194.09729
Heavy Atoms 13
Complexity 158.0

Chemical Identifiers

CAS Number 22429-12-5
SMILES CN1CCN(P1C2=CC=CC=C2)C
InChIKey CYKFZCQRONDMOZ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Electronic Chemicals (1 patents) Heterocyclic Building Blocks (27 patents) Organic Building Blocks (5 patents) Pharmaceutical Intermediates (11 patents) +1 more

Product Overview

Corey-hopkins reagent (CAS 22429-12-5), with molecular formula C10H15N2P and molecular weight 194.10 g/mol. IUPAC: 1,3-dimethyl-2-phenyl-1,3,2-diazaphospholidine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Corey-hopkins reagent

XLogP
1.7
TPSA (Topological Polar Surface Area)
6.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
13
Complexity
158.0
Exact Mass
194.09729
Monoisotopic Mass
194.09729
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Corey-hopkins reagent

The XLogP value of 1.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Corey-hopkins reagent. With a topological polar surface area (TPSA) of 6.5 Ų, Corey-hopkins reagent exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Corey-hopkins reagent has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Corey-hopkins reagent?

The CAS number of Corey-hopkins reagent is 22429-12-5.

What is the molecular formula of Corey-hopkins reagent?

The molecular formula of Corey-hopkins reagent is C10H15N2P.

What is the molecular weight of Corey-hopkins reagent?

The molecular weight of Corey-hopkins reagent is 194.10 g/mol.

Where can I buy Corey-hopkins reagent?

You can request a quote for Corey-hopkins reagent directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Corey-hopkins reagent?

Yes, KEHONG BIO provides custom synthesis services for Corey-hopkins reagent and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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