Ripasudil
TL;DR: Ripasudil (CAS 223645-67-8) is a chemical compound with molecular formula C15H18FN3O2S and molecular weight 323.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-fluoro-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline
Also Known As: Ripasudil, K-115 free base, k115 Free base, glanatec, Ripasudil free base
| Molecular Formula | C15H18FN3O2S |
|---|---|
| Molecular Weight | 323.11 g/mol |
| LogP | 1.7464 |
| Topological Polar Surface Area | 62.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 323.11038 |
| Heavy Atoms | 22 |
| Complexity | 789.2242 |
Chemical Identifiers
| CAS Number | 223645-67-8 |
|---|---|
| SMILES | C[C@H]1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)F |
Product Overview
Ripasudil (CAS 223645-67-8), with molecular formula C15H18FN3O2S and molecular weight 323.11 g/mol. IUPAC: 4-fluoro-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline.
Chemical Property Profile of Ripasudil
Property Insights of Ripasudil
The XLogP value of 1.7464 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Ripasudil. The TPSA of 62.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Ripasudil. Following Lipinski's Rule of Five, Ripasudil has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ripasudil?
The CAS number of Ripasudil is 223645-67-8.
What is the molecular formula of Ripasudil?
The molecular formula of Ripasudil is C15H18FN3O2S.
What is the molecular weight of Ripasudil?
The molecular weight of Ripasudil is 323.11 g/mol.
Where can I buy Ripasudil?
You can request a quote for Ripasudil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ripasudil?
Yes, KEHONG BIO provides custom synthesis services for Ripasudil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.