Apazone Dihydrate structure

Apazone Dihydrate

TL;DR: Apazone Dihydrate (CAS 22304-30-9) is a chemical compound with molecular formula C16H24N4O4 and molecular weight 336.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-(dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione;dihydrate

Also Known As: Apazone dihydrate, Prolixan, Tolyprin, Rheumox, Azapropazone dihydrate

CAS: 22304-30-9
Molecular Formula C16H24N4O4
Molecular Weight 336.18 g/mol
LogP 0.41
Topological Polar Surface Area 58.2 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 3
Exact Mass 336.17975
Heavy Atoms 24
Complexity 516.0

Chemical Identifiers

CAS Number 22304-30-9
SMILES CCCC1C(=O)N2C3=C(C=CC(=C3)C)N=C(N2C1=O)N(C)C.O.O
InChIKey LLMGYOJUHDRDFJ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (11 patents)

Product Overview

Apazone Dihydrate (CAS 22304-30-9), with molecular formula C16H24N4O4 and molecular weight 336.18 g/mol. IUPAC: 5-(dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione;dihydrate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Apazone Dihydrate

XLogP
0.41
TPSA (Topological Polar Surface Area)
58.2
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
3
Heavy Atoms
24
Complexity
516.0
Exact Mass
336.17975
Monoisotopic Mass
336.17975
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Apazone Dihydrate

The XLogP value of 0.41 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Apazone Dihydrate. With a topological polar surface area (TPSA) of 58.2 Ų, Apazone Dihydrate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Apazone Dihydrate has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Apazone Dihydrate?

The CAS number of Apazone Dihydrate is 22304-30-9.

What is the molecular formula of Apazone Dihydrate?

The molecular formula of Apazone Dihydrate is C16H24N4O4.

What is the molecular weight of Apazone Dihydrate?

The molecular weight of Apazone Dihydrate is 336.18 g/mol.

Where can I buy Apazone Dihydrate?

You can request a quote for Apazone Dihydrate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Apazone Dihydrate?

Yes, KEHONG BIO provides custom synthesis services for Apazone Dihydrate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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