4-Cyano-3-fluorobenzyl bromide structure

4-Cyano-3-fluorobenzyl bromide

TL;DR: 4-Cyano-3-fluorobenzyl bromide (CAS 222978-03-2) is a chemical compound with molecular formula C8H5BrFN and molecular weight 212.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(bromomethyl)-2-fluorobenzonitrile

Also Known As: 4-(bromomethyl)-2-fluorobenzonitrile, 4-Cyano-3-fluorobenzyl bromide, 4-bromomethyl-2-fluoro-benzonitrile, Trelagliptin Impurity 9, 4-Bromomethyl-2-fluorobenzonitrile

CAS: 222978-03-2
Molecular Formula C8H5BrFN
Molecular Weight 212.96 g/mol
LogP 2.59228
Topological Polar Surface Area 23.79 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 1
Exact Mass 212.95894
Heavy Atoms 11
Complexity 303.45062

Chemical Identifiers

CAS Number 222978-03-2
SMILES C1=CC(=C(C=C1CBr)F)C#N

Product Overview

4-Cyano-3-fluorobenzyl bromide (CAS 222978-03-2), with molecular formula C8H5BrFN and molecular weight 212.96 g/mol. IUPAC: 4-(bromomethyl)-2-fluorobenzonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 4-Cyano-3-fluorobenzyl bromide

XLogP
2.59228
TPSA (Topological Polar Surface Area)
23.79
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
1
Heavy Atoms
11
Complexity
303.45062
Exact Mass
212.95894
Monoisotopic Mass
212.95894
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Cyano-3-fluorobenzyl bromide

The XLogP value of 2.59228 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Cyano-3-fluorobenzyl bromide. With a topological polar surface area (TPSA) of 23.79 Ų, 4-Cyano-3-fluorobenzyl bromide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Cyano-3-fluorobenzyl bromide has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Cyano-3-fluorobenzyl bromide?

The CAS number of 4-Cyano-3-fluorobenzyl bromide is 222978-03-2.

What is the molecular formula of 4-Cyano-3-fluorobenzyl bromide?

The molecular formula of 4-Cyano-3-fluorobenzyl bromide is C8H5BrFN.

What is the molecular weight of 4-Cyano-3-fluorobenzyl bromide?

The molecular weight of 4-Cyano-3-fluorobenzyl bromide is 212.96 g/mol.

Where can I buy 4-Cyano-3-fluorobenzyl bromide?

You can request a quote for 4-Cyano-3-fluorobenzyl bromide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Cyano-3-fluorobenzyl bromide?

Yes, KEHONG BIO provides custom synthesis services for 4-Cyano-3-fluorobenzyl bromide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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