5'-Amino-2',5'-dideoxy-2-O-ethyluridine
TL;DR: 5'-Amino-2',5'-dideoxy-2-O-ethyluridine (CAS 222737-86-2) is a chemical compound with molecular formula C11H17N3O4 and molecular weight 255.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxyoxolan-2-yl]-2-ethoxypyrimidin-4-one
Also Known As: 5'-Amino-2',5'-dideoxy-2-O-ethyluridine, J1.129.791I, uridine, 5'-amino-2',5'-dideoxy-2-O-ethyl-, 1-[5-(Aminomethyl)-4-hydroxyoxolan-2-yl]-2-ethoxyhydropyrimidin-4-one, 1-(5-Amino-2,5-dideoxy-beta-D-erythro-pentofuranosyl)-2-ethoxypyrimidine-4(1H)-one
| Molecular Formula | C11H17N3O4 |
|---|---|
| Molecular Weight | 255.12 g/mol |
| LogP | -0.7 |
| Topological Polar Surface Area | 97.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 255.1219 |
| Heavy Atoms | 18 |
| Complexity | 382.0 |
Chemical Identifiers
| CAS Number | 222737-86-2 |
|---|---|
| SMILES | CCOC1=NC(=O)C=CN1[C@H]2C[C@@H]([C@H](O2)CN)O |
| InChIKey | LLBXSMAQCMQQCD-QXFUBDJGSA-N |
Product Overview
5'-Amino-2',5'-dideoxy-2-O-ethyluridine (CAS 222737-86-2), with molecular formula C11H17N3O4 and molecular weight 255.12 g/mol. IUPAC: 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxyoxolan-2-yl]-2-ethoxypyrimidin-4-one.
Chemical Property Profile of 5'-Amino-2',5'-dideoxy-2-O-ethyluridine
Property Insights of 5'-Amino-2',5'-dideoxy-2-O-ethyluridine
The XLogP value of -0.7 indicates that 5'-Amino-2',5'-dideoxy-2-O-ethyluridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 97.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 5'-Amino-2',5'-dideoxy-2-O-ethyluridine. Following Lipinski's Rule of Five, 5'-Amino-2',5'-dideoxy-2-O-ethyluridine has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5'-Amino-2',5'-dideoxy-2-O-ethyluridine?
The CAS number of 5'-Amino-2',5'-dideoxy-2-O-ethyluridine is 222737-86-2.
What is the molecular formula of 5'-Amino-2',5'-dideoxy-2-O-ethyluridine?
The molecular formula of 5'-Amino-2',5'-dideoxy-2-O-ethyluridine is C11H17N3O4.
What is the molecular weight of 5'-Amino-2',5'-dideoxy-2-O-ethyluridine?
The molecular weight of 5'-Amino-2',5'-dideoxy-2-O-ethyluridine is 255.12 g/mol.
Where can I buy 5'-Amino-2',5'-dideoxy-2-O-ethyluridine?
You can request a quote for 5'-Amino-2',5'-dideoxy-2-O-ethyluridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5'-Amino-2',5'-dideoxy-2-O-ethyluridine?
Yes, KEHONG BIO provides custom synthesis services for 5'-Amino-2',5'-dideoxy-2-O-ethyluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.