5'-Azido-2',5'-dideoxy-2-O-ethyluridine
TL;DR: 5'-Azido-2',5'-dideoxy-2-O-ethyluridine (CAS 222737-82-8) is a chemical compound with molecular formula C11H15N5O4 and molecular weight 281.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5R)-5-(azidomethyl)-4-hydroxyoxolan-2-yl]-2-ethoxypyrimidin-4-one
Also Known As: 5'-Azido-2',5'-dideoxy-2-O-ethyluridine, J1.129.782J, uridine, 5'-azido-2',5'-dideoxy-2-O-ethyl-, 1-(5-Azido-2,5-dideoxy-beta-D-erythro-pentofuranosyl)-2-ethoxypyrimidine-4(1H)-one, 1-[(2R,4S,5R)-5-(azidomethyl)-4-hydroxy-tetrahydrofuran-2-yl]-2-ethoxy-pyrimidin-4-one
| Molecular Formula | C11H15N5O4 |
|---|---|
| Molecular Weight | 281.11 g/mol |
| LogP | 0.7 |
| Topological Polar Surface Area | 85.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 281.1124 |
| Heavy Atoms | 20 |
| Complexity | 485.0 |
Chemical Identifiers
| CAS Number | 222737-82-8 |
|---|---|
| SMILES | CCOC1=NC(=O)C=CN1[C@H]2C[C@@H]([C@H](O2)CN=[N+]=[N-])O |
| InChIKey | ONLIRFNQXICNBW-QXFUBDJGSA-N |
Product Overview
5'-Azido-2',5'-dideoxy-2-O-ethyluridine (CAS 222737-82-8), with molecular formula C11H15N5O4 and molecular weight 281.11 g/mol. IUPAC: 1-[(2R,4S,5R)-5-(azidomethyl)-4-hydroxyoxolan-2-yl]-2-ethoxypyrimidin-4-one.
Chemical Property Profile of 5'-Azido-2',5'-dideoxy-2-O-ethyluridine
Property Insights of 5'-Azido-2',5'-dideoxy-2-O-ethyluridine
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5'-Azido-2',5'-dideoxy-2-O-ethyluridine. The TPSA of 85.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 5'-Azido-2',5'-dideoxy-2-O-ethyluridine. Following Lipinski's Rule of Five, 5'-Azido-2',5'-dideoxy-2-O-ethyluridine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5'-Azido-2',5'-dideoxy-2-O-ethyluridine?
The CAS number of 5'-Azido-2',5'-dideoxy-2-O-ethyluridine is 222737-82-8.
What is the molecular formula of 5'-Azido-2',5'-dideoxy-2-O-ethyluridine?
The molecular formula of 5'-Azido-2',5'-dideoxy-2-O-ethyluridine is C11H15N5O4.
What is the molecular weight of 5'-Azido-2',5'-dideoxy-2-O-ethyluridine?
The molecular weight of 5'-Azido-2',5'-dideoxy-2-O-ethyluridine is 281.11 g/mol.
Where can I buy 5'-Azido-2',5'-dideoxy-2-O-ethyluridine?
You can request a quote for 5'-Azido-2',5'-dideoxy-2-O-ethyluridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5'-Azido-2',5'-dideoxy-2-O-ethyluridine?
Yes, KEHONG BIO provides custom synthesis services for 5'-Azido-2',5'-dideoxy-2-O-ethyluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.