5-(Trifluoromethyl)picolinamide
TL;DR: 5-(Trifluoromethyl)picolinamide (CAS 22245-86-9) is a chemical compound with molecular formula C7H5F3N2O and molecular weight 190.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(trifluoromethyl)pyridine-2-carboxamide
Also Known As: 5-(Trifluoromethyl)picolinamide, 5-(trifluoromethyl)pyridine-2-carboxamide, 2-Pyridinecarboxamide, 5-(trifluoromethyl)-, 5-Trifluoromethylpyridine-2-carboxamide, 5-trifluoromethyl-pyridine-2-carboxylic acid amide
| Molecular Formula | C7H5F3N2O |
|---|---|
| Molecular Weight | 190.04 g/mol |
| LogP | 1.1993 |
| Topological Polar Surface Area | 55.98 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 190.0354 |
| Heavy Atoms | 13 |
| Complexity | 317.5047 |
Chemical Identifiers
| CAS Number | 22245-86-9 |
|---|---|
| SMILES | C1=CC(=NC=C1C(F)(F)F)C(=O)N |
Product Overview
5-(Trifluoromethyl)picolinamide (CAS 22245-86-9), with molecular formula C7H5F3N2O and molecular weight 190.04 g/mol. IUPAC: 5-(trifluoromethyl)pyridine-2-carboxamide.
Chemical Property Profile of 5-(Trifluoromethyl)picolinamide
Property Insights of 5-(Trifluoromethyl)picolinamide
The XLogP value of 1.1993 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(Trifluoromethyl)picolinamide. With a topological polar surface area (TPSA) of 55.98 Ų, 5-(Trifluoromethyl)picolinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(Trifluoromethyl)picolinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(Trifluoromethyl)picolinamide?
The CAS number of 5-(Trifluoromethyl)picolinamide is 22245-86-9.
What is the molecular formula of 5-(Trifluoromethyl)picolinamide?
The molecular formula of 5-(Trifluoromethyl)picolinamide is C7H5F3N2O.
What is the molecular weight of 5-(Trifluoromethyl)picolinamide?
The molecular weight of 5-(Trifluoromethyl)picolinamide is 190.04 g/mol.
Where can I buy 5-(Trifluoromethyl)picolinamide?
You can request a quote for 5-(Trifluoromethyl)picolinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(Trifluoromethyl)picolinamide?
Yes, KEHONG BIO provides custom synthesis services for 5-(Trifluoromethyl)picolinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.