Ono-LB-457 structure

Ono-LB-457

TL;DR: Ono-LB-457 (CAS 2222579-49-7) is a chemical compound with molecular formula C27H34O7 and molecular weight 470.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-[2-(2-carboxyethyl)-3-[(E)-6-(4-methoxyphenyl)hex-5-enoxy]phenoxy]pentanoic acid

Also Known As: Ono-LB-457, Ono 4057, ONO-LB 457, ONO-LB457, HY-U00252

CAS: 2222579-49-7
Molecular Formula C27H34O7
Molecular Weight 470.23 g/mol
LogP 5.6086
Topological Polar Surface Area 102.29 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 17
Exact Mass 470.23044
Heavy Atoms 34
Complexity 919.07587

Chemical Identifiers

CAS Number 2222579-49-7
SMILES COC1=CC=C(C=C1)/C=C/CCCCOC2=C(C(=CC=C2)OCCCCC(=O)O)CCC(=O)O

Product Overview

Ono-LB-457 (CAS 2222579-49-7), with molecular formula C27H34O7 and molecular weight 470.23 g/mol. IUPAC: 5-[2-(2-carboxyethyl)-3-[(E)-6-(4-methoxyphenyl)hex-5-enoxy]phenoxy]pentanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Ono-LB-457

XLogP
5.6086
TPSA (Topological Polar Surface Area)
102.29
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
17
Heavy Atoms
34
Complexity
919.07587
Exact Mass
470.23044
Monoisotopic Mass
470.23044
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ono-LB-457

The XLogP value of 5.6086 indicates that Ono-LB-457 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 102.29 Ų falls within the moderate polarity range, balancing permeability and solubility for Ono-LB-457. Following Lipinski's Rule of Five, Ono-LB-457 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ono-LB-457?

The CAS number of Ono-LB-457 is 2222579-49-7.

What is the molecular formula of Ono-LB-457?

The molecular formula of Ono-LB-457 is C27H34O7.

What is the molecular weight of Ono-LB-457?

The molecular weight of Ono-LB-457 is 470.23 g/mol.

Where can I buy Ono-LB-457?

You can request a quote for Ono-LB-457 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ono-LB-457?

Yes, KEHONG BIO provides custom synthesis services for Ono-LB-457 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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