Tadalafil Impurity 78
TL;DR: Tadalafil Impurity 78 (CAS 22220-03-7) is a chemical compound with molecular formula C13H11F3N2O3 and molecular weight 300.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-3-(1H-indol-3-yl)-2-[(2,2,2-trifluoroacetyl)amino]propanoic acid
Also Known As: Tadalafil Impurity 78, BAS 00227696, (2R)-3-(1H-indol-3-yl)-2-(trifluoroacetamido)propanoic acid, (2R)-3-(1H-indol-3-yl)-2-[(2,2,2-trifluoroacetyl)amino]propanoic acid
| Molecular Formula | C13H11F3N2O3 |
|---|---|
| Molecular Weight | 300.07 g/mol |
| LogP | 1.8421 |
| Topological Polar Surface Area | 82.19 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 300.07217 |
| Heavy Atoms | 21 |
| Complexity | 678.5965 |
Chemical Identifiers
| CAS Number | 22220-03-7 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2)C[C@H](C(=O)O)NC(=O)C(F)(F)F |
Product Overview
Tadalafil Impurity 78 (CAS 22220-03-7), with molecular formula C13H11F3N2O3 and molecular weight 300.07 g/mol. IUPAC: (2R)-3-(1H-indol-3-yl)-2-[(2,2,2-trifluoroacetyl)amino]propanoic acid.
Chemical Property Profile of Tadalafil Impurity 78
Property Insights of Tadalafil Impurity 78
The XLogP value of 1.8421 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tadalafil Impurity 78. The TPSA of 82.19 Ų falls within the moderate polarity range, balancing permeability and solubility for Tadalafil Impurity 78. Following Lipinski's Rule of Five, Tadalafil Impurity 78 has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tadalafil Impurity 78?
The CAS number of Tadalafil Impurity 78 is 22220-03-7.
What is the molecular formula of Tadalafil Impurity 78?
The molecular formula of Tadalafil Impurity 78 is C13H11F3N2O3.
What is the molecular weight of Tadalafil Impurity 78?
The molecular weight of Tadalafil Impurity 78 is 300.07 g/mol.
Where can I buy Tadalafil Impurity 78?
You can request a quote for Tadalafil Impurity 78 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tadalafil Impurity 78?
Yes, KEHONG BIO provides custom synthesis services for Tadalafil Impurity 78 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.