Mycolactone structure

Mycolactone

TL;DR: Mycolactone (CAS 222050-77-3) is a chemical compound with molecular formula C44H70O9 and molecular weight 742.50 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(6S,7S,9E,12R)-12-[(E,2S,6R,7R,9R)-7,9-dihydroxy-4,6-dimethyldec-4-en-2-yl]-7,9-dimethyl-2-oxo-1-oxacyclododec-9-en-6-yl] (2E,4E,6E,8E,10E,12S,13S,15S)-12,13,15-trihydroxy-4,6,10-trimethylhexadeca-2,4,6,8,10-pentaenoate

Also Known As: Mycolactone, [(6S,7S,9E,12R)-12-[(E,2S,6R,7R,9R)-7,9-dihydroxy-4,6-dimethyldec-4-en-2-yl]-7,9-dimethyl-2-oxo-1-oxacyclododec-9-en-6-yl] (2E,4E,6E,8E,10E,12S,13S,15S)-12,13,15-trihydroxy-4,6,10-trimethylhexadeca-2,4,6,8,10-pentaenoate, ((6S,7S,9E,12R)-12-((E,1S,5R,6R,8R)-6,8-dihydroxy-1,3,5-trimethyl-non-3-enyl)-7,9-dimethyl-2-oxo-1-oxacyclododec-9-en-6-yl) (2E,4E,6E,8E,10E,12S,13S,15S)-12,13,15-trihydroxy-4,6,10-trimethyl-hexadeca-2,4,6,8,10-pentaenoate, (6S,7S,9E,12R)-12-[(2S,4E,6R,7R,9R)-7,9-dihydroxy-4,6-dimethyldec-4-en-2-yl]-7,9-dimethyl-2-oxo-1-oxacyclododec-9-en-6-yl (2E,4E,6E,8E,10E,12S,13S,15S)-12,13,15-trihydroxy-4,6,10-trimethylhexadeca-2,4,6,8,10-pentaenoate, [(6~{S},7~{S},9~{Z},12~{R})-12-[(~{Z},2~{S},6~{R},7~{R},9~{R})-4,6-dimethyl-7,9-bis(oxidanyl)dec-4-en-2-yl]-7,9-dimethyl-2-oxidanylidene-1-oxacyclododec-9-en-6-yl] (2~{E},4~{E},6~{E},8~{E},10~{E},12~{S},13~{S},15~{S})-4,6,10-trimethyl-12,13,15-tris(oxidanyl)hexadeca-2,4,6,8,10-pentaenoate

CAS: 222050-77-3
Molecular Formula C44H70O9
Molecular Weight 742.50 g/mol
LogP 7.5409
Topological Polar Surface Area 153.75 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 9
Rotatable Bonds 17
Exact Mass 742.502
Heavy Atoms 53
Complexity 1346.0103

Chemical Identifiers

CAS Number 222050-77-3
SMILES C[C@H]1C/C(=C/C[C@@H](OC(=O)CCC[C@@H]1OC(=O)/C=C/C(=C/C(=C/C=C/C(=C/[C@@H]([C@H](C[C@H](C)O)O)O)/C)/C)/C)[C@@H](C)C/C(=C/[C@@H](C)[C@@H](C[C@@H](C)O)O)/C)/C

Product Overview

Mycolactone (CAS 222050-77-3), with molecular formula C44H70O9 and molecular weight 742.50 g/mol. IUPAC: [(6S,7S,9E,12R)-12-[(E,2S,6R,7R,9R)-7,9-dihydroxy-4,6-dimethyldec-4-en-2-yl]-7,9-dimethyl-2-oxo-1-oxacyclododec-9-en-6-yl] (2E,4E,6E,8E,10E,12S,13S,15S)-12,13,15-trihydroxy-4,6,10-trimethylhexadeca-2,4,6,8,10-pentaenoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Mycolactone

XLogP
7.5409
TPSA (Topological Polar Surface Area)
153.75
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
9
Rotatable Bonds
17
Heavy Atoms
53
Complexity
1346.0103
Exact Mass
742.502
Monoisotopic Mass
742.502
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Mycolactone

The XLogP value of 7.5409 indicates that Mycolactone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 153.75 Ų indicates high polarity, suggesting Mycolactone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Mycolactone has 5 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Mycolactone?

The CAS number of Mycolactone is 222050-77-3.

What is the molecular formula of Mycolactone?

The molecular formula of Mycolactone is C44H70O9.

What is the molecular weight of Mycolactone?

The molecular weight of Mycolactone is 742.50 g/mol.

Where can I buy Mycolactone?

You can request a quote for Mycolactone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Mycolactone?

Yes, KEHONG BIO provides custom synthesis services for Mycolactone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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