Alamifovir
TL;DR: Alamifovir (CAS 22177-92-0) is a chemical compound with molecular formula C18H18F6N5O4PS and molecular weight 545.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
9-[2-[bis(2,2,2-trifluoroethoxy)phosphorylmethoxy]ethyl]-6-phenylsulfanylpurin-2-amine
Also Known As: Alamifovir, Alamifovir (MCC478), I06-2336, Phosphonic acid,P-[[2-[2-amino-6-[(4-methoxyphenyl)thio]-9H-purin-9-yl]ethoxy]methyl]-,bis(2,2,2-trifluoroethyl) ester, bis(2,2,2-trifluoroethyl)({2-[2-amino-6-(phenylsulfanyl)-9h-purin-9-yl]ethoxy}methyl)phosphonate
| Molecular Formula | C18H18F6N5O4PS |
|---|---|
| Molecular Weight | 545.07 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 140.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 11 |
| Exact Mass | 545.07214 |
| Heavy Atoms | 35 |
| Complexity | 696.0 |
Chemical Identifiers
| CAS Number | 22177-92-0 |
|---|---|
| SMILES | C1=CC=C(C=C1)SC2=NC(=NC3=C2N=CN3CCOCP(=O)(OCC(F)(F)F)OCC(F)(F)F)N |
| InChIKey | JJLWXCPEQYXFFT-UHFFFAOYSA-N |
Product Overview
Alamifovir (CAS 22177-92-0), with molecular formula C18H18F6N5O4PS and molecular weight 545.07 g/mol. IUPAC: 9-[2-[bis(2,2,2-trifluoroethoxy)phosphorylmethoxy]ethyl]-6-phenylsulfanylpurin-2-amine.
Chemical Property Profile of Alamifovir
Property Insights of Alamifovir
The XLogP value of 3.5 indicates that Alamifovir is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 140.0 Ų indicates high polarity, suggesting Alamifovir may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Alamifovir has 1 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Alamifovir?
The CAS number of Alamifovir is 22177-92-0.
What is the molecular formula of Alamifovir?
The molecular formula of Alamifovir is C18H18F6N5O4PS.
What is the molecular weight of Alamifovir?
The molecular weight of Alamifovir is 545.07 g/mol.
Where can I buy Alamifovir?
You can request a quote for Alamifovir directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Alamifovir?
Yes, KEHONG BIO provides custom synthesis services for Alamifovir and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.