5,7-dibromo-3,3-difluoro-1H-indol-2-one
TL;DR: 5,7-dibromo-3,3-difluoro-1H-indol-2-one (CAS 221665-92-5) is a chemical compound with molecular formula C8H3Br2F2NO and molecular weight 324.85 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5,7-dibromo-3,3-difluoro-1H-indol-2-one
Also Known As: 5,7-dibromo-3,3-difluoro-1H-indol-2-one, 5,7-Dibromo-3,3-difluoroindolin-2-one, J1.048.759E, 3,3-Difluoro-5,7-dibromo-1H-indole-2(3H)-one, 5,7-dibromo-3,3-difluoro-2,3-dihydro-1H-indol-2-one
| Molecular Formula | C8H3Br2F2NO |
|---|---|
| Molecular Weight | 324.85 g/mol |
| LogP | 3.2555 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 324.85495 |
| Heavy Atoms | 14 |
| Complexity | 433.5946 |
Chemical Identifiers
| CAS Number | 221665-92-5 |
|---|---|
| SMILES | C1=C(C=C(C2=C1C(C(=O)N2)(F)F)Br)Br |
Product Overview
5,7-dibromo-3,3-difluoro-1H-indol-2-one (CAS 221665-92-5), with molecular formula C8H3Br2F2NO and molecular weight 324.85 g/mol. IUPAC: 5,7-dibromo-3,3-difluoro-1H-indol-2-one.
Chemical Property Profile of 5,7-dibromo-3,3-difluoro-1H-indol-2-one
Property Insights of 5,7-dibromo-3,3-difluoro-1H-indol-2-one
The XLogP value of 3.2555 indicates that 5,7-dibromo-3,3-difluoro-1H-indol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, 5,7-dibromo-3,3-difluoro-1H-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5,7-dibromo-3,3-difluoro-1H-indol-2-one has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5,7-dibromo-3,3-difluoro-1H-indol-2-one?
The CAS number of 5,7-dibromo-3,3-difluoro-1H-indol-2-one is 221665-92-5.
What is the molecular formula of 5,7-dibromo-3,3-difluoro-1H-indol-2-one?
The molecular formula of 5,7-dibromo-3,3-difluoro-1H-indol-2-one is C8H3Br2F2NO.
What is the molecular weight of 5,7-dibromo-3,3-difluoro-1H-indol-2-one?
The molecular weight of 5,7-dibromo-3,3-difluoro-1H-indol-2-one is 324.85 g/mol.
Where can I buy 5,7-dibromo-3,3-difluoro-1H-indol-2-one?
You can request a quote for 5,7-dibromo-3,3-difluoro-1H-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5,7-dibromo-3,3-difluoro-1H-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 5,7-dibromo-3,3-difluoro-1H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.