(Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide structure

(Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide

TL;DR: (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide (CAS 221335-86-0) is a chemical compound with molecular formula C11H8ClNOS and molecular weight 237.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(4-chlorophenyl)-1-thiophen-2-ylmethanimine oxide

Also Known As: (NZ)-4-chloro-N-oxido-N-[(thiophen-2-yl)methylidene]anilinium, (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide, N-(4-chlorophenyl)-1-thiophen-2-ylmethanimine oxide, amino(4-chlorophenyl)(2-thienylmethylene)-1-ol, F1065-0168

CAS: 221335-86-0
Molecular Formula C11H8ClNOS
Molecular Weight 237.00 g/mol
LogP 3.6624
Topological Polar Surface Area 26.07 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 2
Exact Mass 237.00151
Heavy Atoms 15
Complexity 461.84296

Chemical Identifiers

CAS Number 221335-86-0
SMILES C1=CSC(=C1)/C=[N+](/C2=CC=C(C=C2)Cl)\[O-]

Product Overview

(Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide (CAS 221335-86-0), with molecular formula C11H8ClNOS and molecular weight 237.00 g/mol. IUPAC: N-(4-chlorophenyl)-1-thiophen-2-ylmethanimine oxide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide

XLogP
3.6624
TPSA (Topological Polar Surface Area)
26.07
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
15
Complexity
461.84296
Exact Mass
237.00151
Monoisotopic Mass
237.00151
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide

The XLogP value of 3.6624 indicates that (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.07 Ų, (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide?

The CAS number of (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide is 221335-86-0.

What is the molecular formula of (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide?

The molecular formula of (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide is C11H8ClNOS.

What is the molecular weight of (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide?

The molecular weight of (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide is 237.00 g/mol.

Where can I buy (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide?

You can request a quote for (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide?

Yes, KEHONG BIO provides custom synthesis services for (Z)-4-chloro-N-(thiophen-2-ylmethylene)aniline oxide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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