Silatecan
TL;DR: Silatecan (CAS 22091-49-2) is a chemical compound with molecular formula C26H30N2O5Si and molecular weight 478.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(19S)-10-[tert-butyl(dimethyl)silyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
Also Known As: Silatecan, DB 67; Silatecan, Silatecan AR-67, AR67, AR 67 cpd
| Molecular Formula | C26H30N2O5Si |
|---|---|
| Molecular Weight | 478.19 g/mol |
| LogP | 3.5007 |
| Topological Polar Surface Area | 101.65 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 478.1924 |
| Heavy Atoms | 34 |
| Complexity | 1450.5372 |
Chemical Identifiers
| CAS Number | 22091-49-2 |
|---|---|
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=C(C=CC(=C5)O)N=C4C3=C2)[Si](C)(C)C(C)(C)C)O |
Product Overview
Silatecan (CAS 22091-49-2), with molecular formula C26H30N2O5Si and molecular weight 478.19 g/mol. IUPAC: (19S)-10-[tert-butyl(dimethyl)silyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione.
Chemical Property Profile of Silatecan
Property Insights of Silatecan
The XLogP value of 3.5007 indicates that Silatecan is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.65 Ų falls within the moderate polarity range, balancing permeability and solubility for Silatecan. Following Lipinski's Rule of Five, Silatecan has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Silatecan?
The CAS number of Silatecan is 22091-49-2.
What is the molecular formula of Silatecan?
The molecular formula of Silatecan is C26H30N2O5Si.
What is the molecular weight of Silatecan?
The molecular weight of Silatecan is 478.19 g/mol.
Where can I buy Silatecan?
You can request a quote for Silatecan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Silatecan?
Yes, KEHONG BIO provides custom synthesis services for Silatecan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.