Trofosfamide
TL;DR: Trofosfamide (CAS 22089-22-1) is a chemical compound with molecular formula C9H18Cl3N2O2P and molecular weight 322.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N,N,3-tris(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine
Also Known As: Trofosfamide, Ixoten, Trophosphamide, Trofosfamid, Trifosfamide
| Molecular Formula | C9H18Cl3N2O2P |
|---|---|
| Molecular Weight | 322.02 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 32.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 322.01715 |
| Heavy Atoms | 17 |
| Complexity | 265.0 |
Chemical Identifiers
| CAS Number | 22089-22-1 |
|---|---|
| SMILES | C1CN(P(=O)(OC1)N(CCCl)CCCl)CCCl |
| InChIKey | UMKFEPPTGMDVMI-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 14 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Trofosfamide (CAS 22089-22-1), with molecular formula C9H18Cl3N2O2P and molecular weight 322.02 g/mol. IUPAC: N,N,3-tris(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine.
Chemical Property Profile of Trofosfamide
Property Insights of Trofosfamide
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trofosfamide. With a topological polar surface area (TPSA) of 32.8 Ų, Trofosfamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trofosfamide has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Trofosfamide?
The CAS number of Trofosfamide is 22089-22-1.
What is the molecular formula of Trofosfamide?
The molecular formula of Trofosfamide is C9H18Cl3N2O2P.
What is the molecular weight of Trofosfamide?
The molecular weight of Trofosfamide is 322.02 g/mol.
Where can I buy Trofosfamide?
You can request a quote for Trofosfamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Trofosfamide?
Yes, KEHONG BIO provides custom synthesis services for Trofosfamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.