![(4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione structure](/static/products/220/220868-60-0.png)
(4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
TL;DR: (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione (CAS 220868-60-0) is a chemical compound with molecular formula C20H14N2O3S and molecular weight 362.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
Also Known As: (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione, 4-benzoyl-3-hydroxy-5-phenyl-1-(thiazol-2-yl)-1h-pyrrol-2(5h)-one, 3-hydroxy-5-phenyl-4-(phenylcarbonyl)-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one
| Molecular Formula | C20H14N2O3S |
|---|---|
| Molecular Weight | 362.07 g/mol |
| LogP | 3.7694 |
| Topological Polar Surface Area | 70.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 362.0725 |
| Heavy Atoms | 26 |
| Complexity | 982.4202 |
Chemical Identifiers
| CAS Number | 220868-60-0 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2/C(=C(/C3=CC=CC=C3)\O)/C(=O)C(=O)N2C4=NC=CS4 |
Product Overview
(4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione (CAS 220868-60-0), with molecular formula C20H14N2O3S and molecular weight 362.07 g/mol. IUPAC: (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione.
Chemical Property Profile of (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
Property Insights of (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
The XLogP value of 3.7694 indicates that (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.5 Ų falls within the moderate polarity range, balancing permeability and solubility for (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione. Following Lipinski's Rule of Five, (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
The CAS number of (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione is 220868-60-0.
What is the molecular formula of (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
The molecular formula of (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione is C20H14N2O3S.
What is the molecular weight of (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
The molecular weight of (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione is 362.07 g/mol.
Where can I buy (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
You can request a quote for (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4E)-4-[hydroxy(phenyl)methylidene]-5-phenyl-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.