Tmc-95A structure

Tmc-95A

TL;DR: Tmc-95A (CAS 220666-21-7) is a chemical compound with molecular formula C33H38N6O10 and molecular weight 678.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(10S,11R,12S,15S,18S)-15-(2-amino-2-oxoethyl)-10,11,23-trihydroxy-18-[[(3S)-3-methyl-2-oxopentanoyl]amino]-9,14,17-trioxo-N-[(Z)-prop-1-enyl]-8,13,16-triazatetracyclo[18.3.1.02,7.06,10]tetracosa-1(23),2(7),3,5,20(24),21-hexaene-12-carboxamide

Also Known As: TMC-95A, TMC 95A, TMC-95 A, J1.280.266H, (10S,11R,12S,15S,18S)-15-(2-amino-2-oxoethyl)-10,11,23-trihydroxy-18-(((3S)-3-methyl-2-oxopentanoyl)amino)-9,14,17-trioxo-N-((Z)-prop-1-enyl)-8,13,16-triazatetracyclo(18.3.1.02,7.06,10)tetracosa-1(23),2(7),3,5,20(24),21-hexaene-12-carboxamide

CAS: 220666-21-7
Molecular Formula C33H38N6O10
Molecular Weight 678.26 g/mol
LogP -1.2893
Topological Polar Surface Area 266.35 Ų
Hydrogen Bond Donors 9
Hydrogen Bond Acceptors 10
Rotatable Bonds 8
Exact Mass 678.26495
Heavy Atoms 49
Complexity 1742.0345

Chemical Identifiers

CAS Number 220666-21-7
SMILES CC[C@H](C)C(=O)C(=O)N[C@H]1CC2=CC(=C(C=C2)O)C3=C4C(=CC=C3)[C@]([C@@H]([C@H](NC(=O)[C@@H](NC1=O)CC(=O)N)C(=O)N/C=C\C)O)(C(=O)N4)O

Product Overview

Tmc-95A (CAS 220666-21-7), with molecular formula C33H38N6O10 and molecular weight 678.26 g/mol. IUPAC: (10S,11R,12S,15S,18S)-15-(2-amino-2-oxoethyl)-10,11,23-trihydroxy-18-[[(3S)-3-methyl-2-oxopentanoyl]amino]-9,14,17-trioxo-N-[(Z)-prop-1-enyl]-8,13,16-triazatetracyclo[18.3.1.02,7.06,10]tetracosa-1(23),2(7),3,5,20(24),21-hexaene-12-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tmc-95A

XLogP
-1.2893
TPSA (Topological Polar Surface Area)
266.35
Hydrogen Bond Donors
9
Hydrogen Bond Acceptors
10
Rotatable Bonds
8
Heavy Atoms
49
Complexity
1742.0345
Exact Mass
678.26495
Monoisotopic Mass
678.26495
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tmc-95A

The XLogP value of -1.2893 indicates that Tmc-95A is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 266.35 Ų indicates high polarity, suggesting Tmc-95A may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tmc-95A has 9 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tmc-95A?

The CAS number of Tmc-95A is 220666-21-7.

What is the molecular formula of Tmc-95A?

The molecular formula of Tmc-95A is C33H38N6O10.

What is the molecular weight of Tmc-95A?

The molecular weight of Tmc-95A is 678.26 g/mol.

Where can I buy Tmc-95A?

You can request a quote for Tmc-95A directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tmc-95A?

Yes, KEHONG BIO provides custom synthesis services for Tmc-95A and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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