Z-Val-Ala-DL-Asp-Fluoromethylketone
TL;DR: Z-Val-Ala-DL-Asp-Fluoromethylketone (CAS 220644-02-0) is a chemical compound with molecular formula C21H28FN3O7 and molecular weight 453.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoic acid
Also Known As: z-vad-FMK, Z-Val-Ala-DL-Asp-Fluoromethylketone, Z-VA-DL-D-FMK, Z-VA-DL-D(OH)-FMK, Z-VAD-FMK, Non-methylated
| Molecular Formula | C21H28FN3O7 |
|---|---|
| Molecular Weight | 453.19 g/mol |
| LogP | 0.9402 |
| Topological Polar Surface Area | 150.9 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 12 |
| Exact Mass | 453.19113 |
| Heavy Atoms | 32 |
| Complexity | 816.8711 |
Chemical Identifiers
| CAS Number | 220644-02-0 |
|---|---|
| SMILES | C[C@@H](C(=O)NC(CC(=O)O)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1 |
Product Overview
Z-Val-Ala-DL-Asp-Fluoromethylketone (CAS 220644-02-0), with molecular formula C21H28FN3O7 and molecular weight 453.19 g/mol. IUPAC: 5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoic acid.
Chemical Property Profile of Z-Val-Ala-DL-Asp-Fluoromethylketone
Property Insights of Z-Val-Ala-DL-Asp-Fluoromethylketone
The XLogP value of 0.9402 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Z-Val-Ala-DL-Asp-Fluoromethylketone. The TPSA of 150.9 Ų indicates high polarity, suggesting Z-Val-Ala-DL-Asp-Fluoromethylketone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Z-Val-Ala-DL-Asp-Fluoromethylketone has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Z-Val-Ala-DL-Asp-Fluoromethylketone?
The CAS number of Z-Val-Ala-DL-Asp-Fluoromethylketone is 220644-02-0.
What is the molecular formula of Z-Val-Ala-DL-Asp-Fluoromethylketone?
The molecular formula of Z-Val-Ala-DL-Asp-Fluoromethylketone is C21H28FN3O7.
What is the molecular weight of Z-Val-Ala-DL-Asp-Fluoromethylketone?
The molecular weight of Z-Val-Ala-DL-Asp-Fluoromethylketone is 453.19 g/mol.
Where can I buy Z-Val-Ala-DL-Asp-Fluoromethylketone?
You can request a quote for Z-Val-Ala-DL-Asp-Fluoromethylketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Z-Val-Ala-DL-Asp-Fluoromethylketone?
Yes, KEHONG BIO provides custom synthesis services for Z-Val-Ala-DL-Asp-Fluoromethylketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.