3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide
TL;DR: 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide (CAS 220545-44-8) is a chemical compound with molecular formula C15H18F4N2O and molecular weight 318.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide
Also Known As: CL 385319, J1.055.177C, 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide, 3-fluoro-N-[2-(piperidin-1-yl)ethyl]-5-(trifluoromethyl)benzamide, N-(2-Piperidinoethyl)-5-fluoro-3-(trifluoromethyl)benzamide
| Molecular Formula | C15H18F4N2O |
|---|---|
| Molecular Weight | 318.14 g/mol |
| LogP | 3.0602 |
| Topological Polar Surface Area | 32.34 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 318.13553 |
| Heavy Atoms | 22 |
| Complexity | 524.764 |
Chemical Identifiers
| CAS Number | 220545-44-8 |
|---|---|
| SMILES | C1CCN(CC1)CCNC(=O)C2=CC(=CC(=C2)F)C(F)(F)F |
Product Overview
3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide (CAS 220545-44-8), with molecular formula C15H18F4N2O and molecular weight 318.14 g/mol. IUPAC: 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide.
Chemical Property Profile of 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide
Property Insights of 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide
The XLogP value of 3.0602 indicates that 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.34 Ų, 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide?
The CAS number of 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide is 220545-44-8.
What is the molecular formula of 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide?
The molecular formula of 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide is C15H18F4N2O.
What is the molecular weight of 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide?
The molecular weight of 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide is 318.14 g/mol.
Where can I buy 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide?
You can request a quote for 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide?
Yes, KEHONG BIO provides custom synthesis services for 3-fluoro-N-(2-piperidin-1-ylethyl)-5-(trifluoromethyl)benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.