ABT-925 anhydrous free base
TL;DR: ABT-925 anhydrous free base (CAS 220519-06-2) is a chemical compound with molecular formula C20H27F3N6OS and molecular weight 456.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[3-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]propylsulfanyl]-1H-pyrimidin-6-one
Also Known As: ABT-925 anhydrous free base, ABT-925 free base, A-437203, A 37203, LU 201640
| Molecular Formula | C20H27F3N6OS |
|---|---|
| Molecular Weight | 456.19 g/mol |
| LogP | 3.1806 |
| Topological Polar Surface Area | 78.01 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 456.19193 |
| Heavy Atoms | 31 |
| Complexity | 903.23804 |
Chemical Identifiers
| CAS Number | 220519-06-2 |
|---|---|
| SMILES | CC(C)(C)C1=NC(=CC(=N1)N2CCN(CC2)CCCSC3=NC=CC(=O)N3)C(F)(F)F |
Product Overview
ABT-925 anhydrous free base (CAS 220519-06-2), with molecular formula C20H27F3N6OS and molecular weight 456.19 g/mol. IUPAC: 2-[3-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]propylsulfanyl]-1H-pyrimidin-6-one.
Chemical Property Profile of ABT-925 anhydrous free base
Property Insights of ABT-925 anhydrous free base
The XLogP value of 3.1806 indicates that ABT-925 anhydrous free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.01 Ų falls within the moderate polarity range, balancing permeability and solubility for ABT-925 anhydrous free base. Following Lipinski's Rule of Five, ABT-925 anhydrous free base has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of ABT-925 anhydrous free base?
The CAS number of ABT-925 anhydrous free base is 220519-06-2.
What is the molecular formula of ABT-925 anhydrous free base?
The molecular formula of ABT-925 anhydrous free base is C20H27F3N6OS.
What is the molecular weight of ABT-925 anhydrous free base?
The molecular weight of ABT-925 anhydrous free base is 456.19 g/mol.
Where can I buy ABT-925 anhydrous free base?
You can request a quote for ABT-925 anhydrous free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for ABT-925 anhydrous free base?
Yes, KEHONG BIO provides custom synthesis services for ABT-925 anhydrous free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.