3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione
TL;DR: 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione (CAS 220460-62-8) is a chemical compound with molecular formula C13H12FN3O3 and molecular weight 277.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(6-amino-3-oxo-1H-isoindol-2-yl)-3-fluoropiperidine-2,6-dione
Also Known As: 3-(5-amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione, 3-(6-amino-3-oxo-1H-isoindol-2-yl)-3-fluoro-piperidine-2,6-dione
| Molecular Formula | C13H12FN3O3 |
|---|---|
| Molecular Weight | 277.09 g/mol |
| LogP | 0.327 |
| Topological Polar Surface Area | 92.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 277.08627 |
| Heavy Atoms | 20 |
| Complexity | 645.7486 |
Chemical Identifiers
| CAS Number | 220460-62-8 |
|---|---|
| SMILES | C1CC(C(=O)NC1=O)(N2CC3=C(C2=O)C=CC(=C3)N)F |
Product Overview
3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione (CAS 220460-62-8), with molecular formula C13H12FN3O3 and molecular weight 277.09 g/mol. IUPAC: 3-(6-amino-3-oxo-1H-isoindol-2-yl)-3-fluoropiperidine-2,6-dione.
Chemical Property Profile of 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione
Property Insights of 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione
The XLogP value of 0.327 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione. The TPSA of 92.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione. Following Lipinski's Rule of Five, 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione?
The CAS number of 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione is 220460-62-8.
What is the molecular formula of 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione?
The molecular formula of 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione is C13H12FN3O3.
What is the molecular weight of 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione?
The molecular weight of 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione is 277.09 g/mol.
Where can I buy 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione?
You can request a quote for 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione?
Yes, KEHONG BIO provides custom synthesis services for 3-(5-Amino-1-oxo-isoindolin-2-yl)-3-fluoro-piperidine-2,6-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.