1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline
TL;DR: 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline (CAS 220460-55-9) is a chemical compound with molecular formula C13H9FN2O4 and molecular weight 276.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(3-fluoro-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Also Known As: Fluorothalidomide, 3-fluorothalidomide, US20250127903, Compound 294, 1,3-dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline, J1.268.458D
| Molecular Formula | C13H9FN2O4 |
|---|---|
| Molecular Weight | 276.05 g/mol |
| LogP | 0.385 |
| Topological Polar Surface Area | 83.55 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 276.05463 |
| Heavy Atoms | 20 |
| Complexity | 637.0899 |
Chemical Identifiers
| CAS Number | 220460-55-9 |
|---|---|
| SMILES | C1CC(C(=O)NC1=O)(N2C(=O)C3=CC=CC=C3C2=O)F |
Product Overview
1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline (CAS 220460-55-9), with molecular formula C13H9FN2O4 and molecular weight 276.05 g/mol. IUPAC: 2-(3-fluoro-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione.
Chemical Property Profile of 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline
Property Insights of 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline
The XLogP value of 0.385 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline. The TPSA of 83.55 Ų falls within the moderate polarity range, balancing permeability and solubility for 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline. Following Lipinski's Rule of Five, 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline?
The CAS number of 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline is 220460-55-9.
What is the molecular formula of 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline?
The molecular formula of 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline is C13H9FN2O4.
What is the molecular weight of 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline?
The molecular weight of 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline is 276.05 g/mol.
Where can I buy 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline?
You can request a quote for 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline?
Yes, KEHONG BIO provides custom synthesis services for 1,3-Dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.