R-146225
TL;DR: R-146225 (CAS 219979-42-7) is a chemical compound with molecular formula C20H12Cl3N5O2S and molecular weight 490.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[3,5-dichloro-4-[(4-chlorophenyl)-pyrimidin-2-ylsulfanylmethyl]phenyl]-1,2,4-triazine-3,5-dione
Also Known As: R-146225, R 146225, J1.434.241I, (-)-R-146225, 1,2,4-Triazine-3,5(2H,4H)-dione, 2-(3,5-dichloro-4-((4-chlorophenyl)(2-pyrimidinylthio)methyl)phenyl)-, (-)-
| Molecular Formula | C20H12Cl3N5O2S |
|---|---|
| Molecular Weight | 490.98 g/mol |
| LogP | 4.5527 |
| Topological Polar Surface Area | 93.53 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 490.97772 |
| Heavy Atoms | 31 |
| Complexity | 1320.5193 |
Chemical Identifiers
| CAS Number | 219979-42-7 |
|---|---|
| SMILES | C1=CN=C(N=C1)SC(C2=CC=C(C=C2)Cl)C3=C(C=C(C=C3Cl)N4C(=O)NC(=O)C=N4)Cl |
Product Overview
R-146225 (CAS 219979-42-7), with molecular formula C20H12Cl3N5O2S and molecular weight 490.98 g/mol. IUPAC: 2-[3,5-dichloro-4-[(4-chlorophenyl)-pyrimidin-2-ylsulfanylmethyl]phenyl]-1,2,4-triazine-3,5-dione.
Chemical Property Profile of R-146225
Property Insights of R-146225
The XLogP value of 4.5527 indicates that R-146225 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 93.53 Ų falls within the moderate polarity range, balancing permeability and solubility for R-146225. Following Lipinski's Rule of Five, R-146225 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of R-146225?
The CAS number of R-146225 is 219979-42-7.
What is the molecular formula of R-146225?
The molecular formula of R-146225 is C20H12Cl3N5O2S.
What is the molecular weight of R-146225?
The molecular weight of R-146225 is 490.98 g/mol.
Where can I buy R-146225?
You can request a quote for R-146225 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for R-146225?
Yes, KEHONG BIO provides custom synthesis services for R-146225 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.