4'-Trifluoromethyl-5-methyluridine
TL;DR: 4'-Trifluoromethyl-5-methyluridine (CAS 219649-53-3) is a chemical compound with molecular formula C11H13F3N2O6 and molecular weight 326.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-(trifluoromethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: 4'-Trifluoromethyl-5-methyluridine, 5-Methyl-4'-C-(trifluoromethyl)uridine, uridine, 5-methyl-4'-C-(trifluoromethyl)-, J1.031.568I, 1-[4-C-(Trifluoromethyl)-beta-D-ribofuranosyl]thymine
| Molecular Formula | C11H13F3N2O6 |
|---|---|
| Molecular Weight | 326.07 g/mol |
| LogP | -1.0 |
| Topological Polar Surface Area | 119.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 326.07257 |
| Heavy Atoms | 22 |
| Complexity | 536.0 |
Chemical Identifiers
| CAS Number | 219649-53-3 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@](O2)(CO)C(F)(F)F)O)O |
| InChIKey | QBCCPAYXNMOHKH-TWOTXZKJSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
4'-Trifluoromethyl-5-methyluridine (CAS 219649-53-3), with molecular formula C11H13F3N2O6 and molecular weight 326.07 g/mol. IUPAC: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-(trifluoromethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 4'-Trifluoromethyl-5-methyluridine
Property Insights of 4'-Trifluoromethyl-5-methyluridine
The XLogP value of -1.0 indicates that 4'-Trifluoromethyl-5-methyluridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 119.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 4'-Trifluoromethyl-5-methyluridine. Following Lipinski's Rule of Five, 4'-Trifluoromethyl-5-methyluridine has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4'-Trifluoromethyl-5-methyluridine?
The CAS number of 4'-Trifluoromethyl-5-methyluridine is 219649-53-3.
What is the molecular formula of 4'-Trifluoromethyl-5-methyluridine?
The molecular formula of 4'-Trifluoromethyl-5-methyluridine is C11H13F3N2O6.
What is the molecular weight of 4'-Trifluoromethyl-5-methyluridine?
The molecular weight of 4'-Trifluoromethyl-5-methyluridine is 326.07 g/mol.
Where can I buy 4'-Trifluoromethyl-5-methyluridine?
You can request a quote for 4'-Trifluoromethyl-5-methyluridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4'-Trifluoromethyl-5-methyluridine?
Yes, KEHONG BIO provides custom synthesis services for 4'-Trifluoromethyl-5-methyluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.