FGFR inhibitors
TL;DR: FGFR inhibitors (CAS 219580-11-7) is a chemical compound with molecular formula C28H41N7O3 and molecular weight 523.33 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
FGFR inhibitors
1-tert-butyl-3-[2-[4-(diethylamino)butylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea
Also Known As: 2fgi, FGFR inhibitors, 1-(tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea, JSPY-st000263, Pyrido[2,3-d]pyrimidine 12
| Molecular Formula | C28H41N7O3 |
|---|---|
| Molecular Weight | 523.33 g/mol |
| LogP | 4.5 |
| Topological Polar Surface Area | 114.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 13 |
| Exact Mass | 523.3271 |
| Heavy Atoms | 38 |
| Complexity | 690.0 |
Chemical Identifiers
| CAS Number | 219580-11-7 |
|---|---|
| SMILES | CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C |
| InChIKey | DXCUKNQANPLTEJ-UHFFFAOYSA-N |
Product Overview
FGFR inhibitors (CAS 219580-11-7), with molecular formula C28H41N7O3 and molecular weight 523.33 g/mol. IUPAC: 1-tert-butyl-3-[2-[4-(diethylamino)butylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea.
Chemical Property Profile of FGFR inhibitors
Property Insights of FGFR inhibitors
The XLogP value of 4.5 indicates that FGFR inhibitors is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 114.0 Ų falls within the moderate polarity range, balancing permeability and solubility for FGFR inhibitors. Following Lipinski's Rule of Five, FGFR inhibitors has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of FGFR inhibitors?
The CAS number of FGFR inhibitors is 219580-11-7.
What is the molecular formula of FGFR inhibitors?
The molecular formula of FGFR inhibitors is C28H41N7O3.
What is the molecular weight of FGFR inhibitors?
The molecular weight of FGFR inhibitors is 523.33 g/mol.
Where can I buy FGFR inhibitors?
You can request a quote for FGFR inhibitors directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for FGFR inhibitors?
Yes, KEHONG BIO provides custom synthesis services for FGFR inhibitors and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.