Noscapine Hydrochloride structure

Noscapine Hydrochloride

TL;DR: Noscapine Hydrochloride (CAS 219533-73-0) is a chemical compound with molecular formula C22H24ClNO7 and molecular weight 449.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride

Also Known As: Noscapine hydrochloride, Noscapine HCl, Noscapine hydrchloride, Tusscapine, noscapine

CAS: 219533-73-0
Molecular Formula C22H24ClNO7
Molecular Weight 449.12 g/mol
LogP 3.3036
Topological Polar Surface Area 75.69 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 8
Rotatable Bonds 4
Exact Mass 449.1241
Heavy Atoms 31
Complexity 1041.25

Chemical Identifiers

CAS Number 219533-73-0
SMILES CN1CCC2=CC3=C(C(=C2[C@@H]1[C@@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.Cl

Product Overview

Noscapine Hydrochloride (CAS 219533-73-0), with molecular formula C22H24ClNO7 and molecular weight 449.12 g/mol. IUPAC: (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Noscapine Hydrochloride

XLogP
3.3036
TPSA (Topological Polar Surface Area)
75.69
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
8
Rotatable Bonds
4
Heavy Atoms
31
Complexity
1041.25
Exact Mass
449.1241
Monoisotopic Mass
449.1241
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Noscapine Hydrochloride

The XLogP value of 3.3036 indicates that Noscapine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.69 Ų falls within the moderate polarity range, balancing permeability and solubility for Noscapine Hydrochloride. Following Lipinski's Rule of Five, Noscapine Hydrochloride has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Noscapine Hydrochloride?

The CAS number of Noscapine Hydrochloride is 219533-73-0.

What is the molecular formula of Noscapine Hydrochloride?

The molecular formula of Noscapine Hydrochloride is C22H24ClNO7.

What is the molecular weight of Noscapine Hydrochloride?

The molecular weight of Noscapine Hydrochloride is 449.12 g/mol.

Where can I buy Noscapine Hydrochloride?

You can request a quote for Noscapine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Noscapine Hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Noscapine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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