Codeine-6-glucuronide structure

Codeine-6-glucuronide

TL;DR: Codeine-6-glucuronide (CAS 219533-59-2) is a chemical compound with molecular formula C24H29NO9 and molecular weight 475.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S,3S,4S,5R,6R)-6-[[(4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

Also Known As: Codeine-6-glucuronide, codeine glucuronide, Codeine-6G, Codeine 6-glucuronide, Codeine 6-beta-D-Glucuronide

CAS: 219533-59-2
Molecular Formula C24H29NO9
Molecular Weight 475.18 g/mol
LogP -0.5824
Topological Polar Surface Area 138.15 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 9
Rotatable Bonds 4
Exact Mass 475.18423
Heavy Atoms 34
Complexity 1045.5151

Chemical Identifiers

CAS Number 219533-59-2
SMILES CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](C=C4)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O

Product Overview

Codeine-6-glucuronide (CAS 219533-59-2), with molecular formula C24H29NO9 and molecular weight 475.18 g/mol. IUPAC: (2S,3S,4S,5R,6R)-6-[[(4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Codeine-6-glucuronide

XLogP
-0.5824
TPSA (Topological Polar Surface Area)
138.15
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
9
Rotatable Bonds
4
Heavy Atoms
34
Complexity
1045.5151
Exact Mass
475.18423
Monoisotopic Mass
475.18423
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Codeine-6-glucuronide

The XLogP value of -0.5824 indicates that Codeine-6-glucuronide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 138.15 Ų falls within the moderate polarity range, balancing permeability and solubility for Codeine-6-glucuronide. Following Lipinski's Rule of Five, Codeine-6-glucuronide has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Codeine-6-glucuronide?

The CAS number of Codeine-6-glucuronide is 219533-59-2.

What is the molecular formula of Codeine-6-glucuronide?

The molecular formula of Codeine-6-glucuronide is C24H29NO9.

What is the molecular weight of Codeine-6-glucuronide?

The molecular weight of Codeine-6-glucuronide is 475.18 g/mol.

Where can I buy Codeine-6-glucuronide?

You can request a quote for Codeine-6-glucuronide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Codeine-6-glucuronide?

Yes, KEHONG BIO provides custom synthesis services for Codeine-6-glucuronide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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