Hydroxyzine Hydrochloride
TL;DR: Hydroxyzine Hydrochloride (CAS 2192-20-3) is a chemical compound with molecular formula C21H29Cl3N2O2 and molecular weight 446.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride
Also Known As: Hydroxyzine dihydrochloride, Hydroxyzine hydrochloride, Orgatrax, Alamon, Atarax
| Molecular Formula | C21H29Cl3N2O2 |
|---|---|
| Molecular Weight | 446.13 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 35.9 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 446.12946 |
| Heavy Atoms | 28 |
| Complexity | 376.0 |
Chemical Identifiers
| CAS Number | 2192-20-3 |
|---|---|
| SMILES | C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl |
| InChIKey | ANOMHKZSQFYSBR-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 12 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Hydroxyzine Hydrochloride (CAS 2192-20-3), with molecular formula C21H29Cl3N2O2 and molecular weight 446.13 g/mol. IUPAC: 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride.
Chemical Property Profile of Hydroxyzine Hydrochloride
Property Insights of Hydroxyzine Hydrochloride
The XLogP value of 3.9 indicates that Hydroxyzine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.9 Ų, Hydroxyzine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Hydroxyzine Hydrochloride has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Hydroxyzine Hydrochloride?
The CAS number of Hydroxyzine Hydrochloride is 2192-20-3.
What is the molecular formula of Hydroxyzine Hydrochloride?
The molecular formula of Hydroxyzine Hydrochloride is C21H29Cl3N2O2.
What is the molecular weight of Hydroxyzine Hydrochloride?
The molecular weight of Hydroxyzine Hydrochloride is 446.13 g/mol.
Where can I buy Hydroxyzine Hydrochloride?
You can request a quote for Hydroxyzine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Hydroxyzine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Hydroxyzine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.