Silodosin
TL;DR: Silodosin (CAS 2182279-45-2) is a chemical compound with molecular formula C25H32F3N3O4 and molecular weight 495.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(3-hydroxypropyl)-5-[2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]-2,3-dihydroindole-7-carboxamide
Also Known As: Silodosin, rac-Silodosin, Rapaflo, Silodosin-d4, Silodosin-d6
| Molecular Formula | C25H32F3N3O4 |
|---|---|
| Molecular Weight | 495.23 g/mol |
| LogP | 3.0711 |
| Topological Polar Surface Area | 97.05 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 13 |
| Exact Mass | 495.2345 |
| Heavy Atoms | 35 |
| Complexity | 1000.4077 |
Chemical Identifiers
| CAS Number | 2182279-45-2 |
|---|---|
| SMILES | CC(CC1=CC2=C(C(=C1)C(=O)N)N(CC2)CCCO)NCCOC3=CC=CC=C3OCC(F)(F)F |
Product Overview
Silodosin (CAS 2182279-45-2), with molecular formula C25H32F3N3O4 and molecular weight 495.23 g/mol. IUPAC: 1-(3-hydroxypropyl)-5-[2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]-2,3-dihydroindole-7-carboxamide.
Chemical Property Profile of Silodosin
Property Insights of Silodosin
The XLogP value of 3.0711 indicates that Silodosin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 97.05 Ų falls within the moderate polarity range, balancing permeability and solubility for Silodosin. Following Lipinski's Rule of Five, Silodosin has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Silodosin?
The CAS number of Silodosin is 2182279-45-2.
What is the molecular formula of Silodosin?
The molecular formula of Silodosin is C25H32F3N3O4.
What is the molecular weight of Silodosin?
The molecular weight of Silodosin is 495.23 g/mol.
Where can I buy Silodosin?
You can request a quote for Silodosin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Silodosin?
Yes, KEHONG BIO provides custom synthesis services for Silodosin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.