O-1057 free base structure

O-1057 free base

TL;DR: O-1057 free base (CAS 216988-52-2) is a chemical compound with molecular formula C32H46N2O4 and molecular weight 522.35 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(6aR,10aR)-3-(6-cyano-2-methylhexan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-yl] 4-morpholin-4-ylbutanoate

Also Known As: O-1057 free base, J1.313.630K, (6aR,10aR)-3-(6-Cyano-2-methylhexan-2-yl)-6,6,9-trimethyl-6H,6ah,7H,10H,10ah-benzo(C)isochromen-1-yl 4-(morpholin-4-yl)butanoate, 4-Morpholinebutanoic acid, (6aR,10aR)-3-(5-cyano-1,1-dimethylpentyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo(b,d)pyran-1-yl ester, (6aR,10aR)-3-(6-cyano-2-methylhexan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-yl 4-morpholinobutanoate

CAS: 216988-52-2
Molecular Formula C32H46N2O4
Molecular Weight 522.35 g/mol
LogP 6.67688
Topological Polar Surface Area 71.79 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 10
Exact Mass 522.34576
Heavy Atoms 38
Complexity 1061.9532

Chemical Identifiers

CAS Number 216988-52-2
SMILES CC1=CC[C@@H]2[C@@H](C1)C3=C(C=C(C=C3OC(=O)CCCN4CCOCC4)C(C)(C)CCCCC#N)OC2(C)C

Product Overview

O-1057 free base (CAS 216988-52-2), with molecular formula C32H46N2O4 and molecular weight 522.35 g/mol. IUPAC: [(6aR,10aR)-3-(6-cyano-2-methylhexan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-yl] 4-morpholin-4-ylbutanoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of O-1057 free base

XLogP
6.67688
TPSA (Topological Polar Surface Area)
71.79
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
10
Heavy Atoms
38
Complexity
1061.9532
Exact Mass
522.34576
Monoisotopic Mass
522.34576
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of O-1057 free base

The XLogP value of 6.67688 indicates that O-1057 free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.79 Ų falls within the moderate polarity range, balancing permeability and solubility for O-1057 free base. Following Lipinski's Rule of Five, O-1057 free base has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of O-1057 free base?

The CAS number of O-1057 free base is 216988-52-2.

What is the molecular formula of O-1057 free base?

The molecular formula of O-1057 free base is C32H46N2O4.

What is the molecular weight of O-1057 free base?

The molecular weight of O-1057 free base is 522.35 g/mol.

Where can I buy O-1057 free base?

You can request a quote for O-1057 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for O-1057 free base?

Yes, KEHONG BIO provides custom synthesis services for O-1057 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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