(4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine
TL;DR: (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine (CAS 21656-92-8) is a chemical compound with molecular formula C11H11F3N2 and molecular weight 228.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-(trifluoromethyl)phenyl]-3,4-dihydro-2H-pyrrol-5-amine
Also Known As: (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine, N-[2-(trifluoromethyl)phenyl]-3,4-dihydro-2H-pyrrol-5-amine
| Molecular Formula | C11H11F3N2 |
|---|---|
| Molecular Weight | 228.09 g/mol |
| LogP | 3.3096 |
| Topological Polar Surface Area | 24.39 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 228.08743 |
| Heavy Atoms | 16 |
| Complexity | 409.93585 |
Chemical Identifiers
| CAS Number | 21656-92-8 |
|---|---|
| SMILES | C1CC(=NC1)NC2=CC=CC=C2C(F)(F)F |
Product Overview
(4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine (CAS 21656-92-8), with molecular formula C11H11F3N2 and molecular weight 228.09 g/mol. IUPAC: N-[2-(trifluoromethyl)phenyl]-3,4-dihydro-2H-pyrrol-5-amine.
Chemical Property Profile of (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine
Property Insights of (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine
The XLogP value of 3.3096 indicates that (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 24.39 Ų, (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine?
The CAS number of (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine is 21656-92-8.
What is the molecular formula of (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine?
The molecular formula of (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine is C11H11F3N2.
What is the molecular weight of (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine?
The molecular weight of (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine is 228.09 g/mol.
Where can I buy (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine?
You can request a quote for (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine?
Yes, KEHONG BIO provides custom synthesis services for (4,5-dihydro-3H-pyrrol-2-yl)-(2-trifluoromethyl-phenyl)-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.