SB 272183 structure

SB 272183

TL;DR: SB 272183 (CAS 216058-27-4) is a chemical compound with molecular formula C29H28ClN5O and molecular weight 497.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-chloro-6-(4-methylpiperazin-1-yl)-N-(4-pyridin-4-ylnaphthalen-1-yl)-2,3-dihydroindole-1-carboxamide

Also Known As: J1.593.833A, 5-chloro-6-(4-methylpiperazin-1-yl)-N-(4-pyridin-4-ylnaphthalen-1-yl)-2,3-dihydroindole-1-carboxamide, 5-chloro-2,3-dihydro-6-(4-methylpiperazin-1-yl)-1-(4-(pyridin-4-yl)naphth-1-ylaminocarbonyl)-1h-indole, 5-chloro-6-(4-methylpiperazin-1-yl)-N-[4-(pyridin-4-yl)naphthalen-1-yl]-2,3-dihydro-1H-indole-1-carboxamide, N-[4-(4-Pyridyl)-1-naphthyl]-5-chloro-6-(4-methylpiperazino)-2,3-dihydro-1H-indole-1-carboxamide

CAS: 216058-27-4
Molecular Formula C29H28ClN5O
Molecular Weight 497.20 g/mol
LogP 5.9016
Topological Polar Surface Area 51.71 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 497.19824
Heavy Atoms 36
Complexity 1432.8114

Chemical Identifiers

CAS Number 216058-27-4
SMILES CN1CCN(CC1)C2=C(C=C3CCN(C3=C2)C(=O)NC4=CC=C(C5=CC=CC=C54)C6=CC=NC=C6)Cl

Product Overview

SB 272183 (CAS 216058-27-4), with molecular formula C29H28ClN5O and molecular weight 497.20 g/mol. IUPAC: 5-chloro-6-(4-methylpiperazin-1-yl)-N-(4-pyridin-4-ylnaphthalen-1-yl)-2,3-dihydroindole-1-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of SB 272183

XLogP
5.9016
TPSA (Topological Polar Surface Area)
51.71
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
36
Complexity
1432.8114
Exact Mass
497.19824
Monoisotopic Mass
497.19824
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of SB 272183

The XLogP value of 5.9016 indicates that SB 272183 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.71 Ų, SB 272183 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, SB 272183 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of SB 272183?

The CAS number of SB 272183 is 216058-27-4.

What is the molecular formula of SB 272183?

The molecular formula of SB 272183 is C29H28ClN5O.

What is the molecular weight of SB 272183?

The molecular weight of SB 272183 is 497.20 g/mol.

Where can I buy SB 272183?

You can request a quote for SB 272183 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for SB 272183?

Yes, KEHONG BIO provides custom synthesis services for SB 272183 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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