Difluoromethylene structure

Difluoromethylene

TL;DR: Difluoromethylene (CAS 2154-59-8) is a chemical compound with molecular formula CF2 and molecular weight 50.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

Also Known As: Difluoromethylene, difluorocarbene, carbon difluoride, difluoromethylidene, Monocarbon difluoride

CAS: 2154-59-8
Molecular Formula CF2
Molecular Weight 50.00 g/mol
LogP 0.92169
Topological Polar Surface Area 0.0 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 0
Rotatable Bonds 0
Exact Mass 49.996807
Heavy Atoms 3
Complexity 2.7548876

Chemical Identifiers

CAS Number 2154-59-8
SMILES [C](F)F

Product Overview

Difluoromethylene (CAS 2154-59-8), with molecular formula CF2 and molecular weight 50.00 g/mol.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Difluoromethylene

XLogP
0.92169
TPSA (Topological Polar Surface Area)
0.0
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
0
Rotatable Bonds
0
Heavy Atoms
3
Complexity
2.7548876
Exact Mass
49.996807
Monoisotopic Mass
49.996807
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Difluoromethylene

The XLogP value of 0.92169 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Difluoromethylene. With a topological polar surface area (TPSA) of 0.0 Ų, Difluoromethylene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Difluoromethylene has 0 hydrogen bond donor(s) and 0 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Difluoromethylene?

The CAS number of Difluoromethylene is 2154-59-8.

What is the molecular formula of Difluoromethylene?

The molecular formula of Difluoromethylene is CF2.

What is the molecular weight of Difluoromethylene?

The molecular weight of Difluoromethylene is 50.00 g/mol.

Where can I buy Difluoromethylene?

You can request a quote for Difluoromethylene directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Difluoromethylene?

Yes, KEHONG BIO provides custom synthesis services for Difluoromethylene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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