Metofoline
TL;DR: Metofoline (CAS 2154-02-1) is a chemical compound with molecular formula C20H24ClNO2 and molecular weight 345.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(4-chlorophenyl)ethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
Also Known As: Metofoline, Methopholine, Metopholine, Versidyne, Mesofolin
| Molecular Formula | C20H24ClNO2 |
|---|---|
| Molecular Weight | 345.15 g/mol |
| LogP | 4.7 |
| Topological Polar Surface Area | 21.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 345.14957 |
| Heavy Atoms | 24 |
| Complexity | 386.0 |
Chemical Identifiers
| CAS Number | 2154-02-1 |
|---|---|
| SMILES | CN1CCC2=CC(=C(C=C2C1CCC3=CC=C(C=C3)Cl)OC)OC |
| InChIKey | YBCPYHQFUMNOJG-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Metofoline (CAS 2154-02-1), with molecular formula C20H24ClNO2 and molecular weight 345.15 g/mol. IUPAC: 1-[2-(4-chlorophenyl)ethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline.
Chemical Property Profile of Metofoline
Property Insights of Metofoline
The XLogP value of 4.7 indicates that Metofoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 21.7 Ų, Metofoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Metofoline has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Metofoline?
The CAS number of Metofoline is 2154-02-1.
What is the molecular formula of Metofoline?
The molecular formula of Metofoline is C20H24ClNO2.
What is the molecular weight of Metofoline?
The molecular weight of Metofoline is 345.15 g/mol.
Where can I buy Metofoline?
You can request a quote for Metofoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Metofoline?
Yes, KEHONG BIO provides custom synthesis services for Metofoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.