8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
TL;DR: 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid (CAS 215122-23-9) is a chemical compound with molecular formula C11H6F4O3 and molecular weight 262.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Also Known As: 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid, 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylicAcid
| Molecular Formula | C11H6F4O3 |
|---|---|
| Molecular Weight | 262.03 g/mol |
| LogP | 2.617 |
| Topological Polar Surface Area | 46.53 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 262.0253 |
| Heavy Atoms | 18 |
| Complexity | 533.58014 |
Chemical Identifiers
| CAS Number | 215122-23-9 |
|---|---|
| SMILES | C1=CC2=C(C(=C1)F)OC(C(=C2)C(=O)O)C(F)(F)F |
Product Overview
8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid (CAS 215122-23-9), with molecular formula C11H6F4O3 and molecular weight 262.03 g/mol. IUPAC: 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid.
Chemical Property Profile of 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Property Insights of 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
The XLogP value of 2.617 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid. With a topological polar surface area (TPSA) of 46.53 Ų, 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid?
The CAS number of 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid is 215122-23-9.
What is the molecular formula of 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid?
The molecular formula of 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid is C11H6F4O3.
What is the molecular weight of 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid?
The molecular weight of 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid is 262.03 g/mol.
Where can I buy 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid?
You can request a quote for 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid?
Yes, KEHONG BIO provides custom synthesis services for 8-fluoro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.