DPC 963 structure

DPC 963

TL;DR: DPC 963 (CAS 21498-52-2) is a chemical compound with molecular formula C14H9F5N2O and molecular weight 316.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(2-cyclopropylethynyl)-5,6-difluoro-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one

Also Known As: DPC 963, Trifluromethylquinazolinone deriv. 13, 4-(cyclopropylethynyl)-5,6-difluoro-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1h)-one, 4-(2-cyclopropylethynyl)-5,6-difluoro-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one, 2(1H)-Quinazolinone, 4-(cyclopropylethynyl)-5,6-difluoro-3,4-dihydro-4-(trifluoromethyl)-

CAS: 21498-52-2
Molecular Formula C14H9F5N2O
Molecular Weight 316.06 g/mol
LogP 3.0
Topological Polar Surface Area 41.1 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 6
Rotatable Bonds 1
Exact Mass 316.0635
Heavy Atoms 22
Complexity 546.0

Chemical Identifiers

CAS Number 21498-52-2
SMILES C1CC1C#CC2(C3=C(C=CC(=C3F)F)NC(=O)N2)C(F)(F)F
InChIKey QCNJQJJFXFJVCX-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (17 patents) Pharmaceutical Intermediates (18 patents)

Product Overview

DPC 963 (CAS 21498-52-2), with molecular formula C14H9F5N2O and molecular weight 316.06 g/mol. IUPAC: 4-(2-cyclopropylethynyl)-5,6-difluoro-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of DPC 963

XLogP
3.0
TPSA (Topological Polar Surface Area)
41.1
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
6
Rotatable Bonds
1
Heavy Atoms
22
Complexity
546.0
Exact Mass
316.0635
Monoisotopic Mass
316.0635
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of DPC 963

The XLogP value of 3.0 indicates that DPC 963 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.1 Ų, DPC 963 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, DPC 963 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of DPC 963?

The CAS number of DPC 963 is 21498-52-2.

What is the molecular formula of DPC 963?

The molecular formula of DPC 963 is C14H9F5N2O.

What is the molecular weight of DPC 963?

The molecular weight of DPC 963 is 316.06 g/mol.

Where can I buy DPC 963?

You can request a quote for DPC 963 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for DPC 963?

Yes, KEHONG BIO provides custom synthesis services for DPC 963 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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