2-Phenyl-4-acetyl-5-bromo-thiazole
TL;DR: 2-Phenyl-4-acetyl-5-bromo-thiazole (CAS 21160-67-8) is a chemical compound with molecular formula C11H8BrNOS and molecular weight 280.95 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(5-bromo-2-phenyl-1,3-thiazol-4-yl)ethanone
Also Known As: 2-Phenyl-4-acetyl-5-bromo-thiazole, 4-acetyl-5-bromo-2-phenylthiazole, 1-(5-Bromo-2-phenyl-1,3-thiazol-4-yl)ethanone, 1-(5-Bromo-2-phenylthiazol-4-yl)ethan-1-one, 1-(5-Bromo-2-phenyl-1,3-thiazol-4-yl)ethanone #
| Molecular Formula | C11H8BrNOS |
|---|---|
| Molecular Weight | 280.95 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 58.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 280.951 |
| Heavy Atoms | 15 |
| Complexity | 243.0 |
Chemical Identifiers
| CAS Number | 21160-67-8 |
|---|---|
| SMILES | CC(=O)C1=C(SC(=N1)C2=CC=CC=C2)Br |
| InChIKey | FHGUZTDYHWCCGU-UHFFFAOYSA-N |
Product Overview
2-Phenyl-4-acetyl-5-bromo-thiazole (CAS 21160-67-8), with molecular formula C11H8BrNOS and molecular weight 280.95 g/mol. IUPAC: 1-(5-bromo-2-phenyl-1,3-thiazol-4-yl)ethanone.
Chemical Property Profile of 2-Phenyl-4-acetyl-5-bromo-thiazole
Property Insights of 2-Phenyl-4-acetyl-5-bromo-thiazole
The XLogP value of 3.7 indicates that 2-Phenyl-4-acetyl-5-bromo-thiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.2 Ų, 2-Phenyl-4-acetyl-5-bromo-thiazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Phenyl-4-acetyl-5-bromo-thiazole has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Phenyl-4-acetyl-5-bromo-thiazole?
The CAS number of 2-Phenyl-4-acetyl-5-bromo-thiazole is 21160-67-8.
What is the molecular formula of 2-Phenyl-4-acetyl-5-bromo-thiazole?
The molecular formula of 2-Phenyl-4-acetyl-5-bromo-thiazole is C11H8BrNOS.
What is the molecular weight of 2-Phenyl-4-acetyl-5-bromo-thiazole?
The molecular weight of 2-Phenyl-4-acetyl-5-bromo-thiazole is 280.95 g/mol.
Where can I buy 2-Phenyl-4-acetyl-5-bromo-thiazole?
You can request a quote for 2-Phenyl-4-acetyl-5-bromo-thiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Phenyl-4-acetyl-5-bromo-thiazole?
Yes, KEHONG BIO provides custom synthesis services for 2-Phenyl-4-acetyl-5-bromo-thiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.