N,N-Bis(trimethylsilyl)trifluoroacetamide
TL;DR: N,N-Bis(trimethylsilyl)trifluoroacetamide (CAS 21149-38-2) is a chemical compound with molecular formula C8H18F3NOSi2 and molecular weight 257.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2,2-trifluoro-N,N-bis(trimethylsilyl)acetamide
Also Known As: Bis(trimethylsilyl)trifluoroacetamide, 2,2,2-Trifluoro-N,N-bis(trimethylsilyl)acetamide, Acetamide, 2,2,2-trifluoro-N,N-bis(trimethylsilyl)-, N,N-BSTFA, Bis(trimethylsilyl)sulfate
| Molecular Formula | C8H18F3NOSi2 |
|---|---|
| Molecular Weight | 257.09 g/mol |
| LogP | 3.05 |
| Topological Polar Surface Area | 20.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 257.0879 |
| Heavy Atoms | 15 |
| Complexity | 238.0 |
Chemical Identifiers
| CAS Number | 21149-38-2 |
|---|---|
| SMILES | C[Si](C)(C)N(C(=O)C(F)(F)F)[Si](C)(C)C |
| InChIKey | RZYHXKLKJRGJGP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 20 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N,N-Bis(trimethylsilyl)trifluoroacetamide (CAS 21149-38-2), with molecular formula C8H18F3NOSi2 and molecular weight 257.09 g/mol. IUPAC: 2,2,2-trifluoro-N,N-bis(trimethylsilyl)acetamide.
Chemical Property Profile of N,N-Bis(trimethylsilyl)trifluoroacetamide
Property Insights of N,N-Bis(trimethylsilyl)trifluoroacetamide
The XLogP value of 3.05 indicates that N,N-Bis(trimethylsilyl)trifluoroacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.3 Ų, N,N-Bis(trimethylsilyl)trifluoroacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N,N-Bis(trimethylsilyl)trifluoroacetamide has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N,N-Bis(trimethylsilyl)trifluoroacetamide?
The CAS number of N,N-Bis(trimethylsilyl)trifluoroacetamide is 21149-38-2.
What is the molecular formula of N,N-Bis(trimethylsilyl)trifluoroacetamide?
The molecular formula of N,N-Bis(trimethylsilyl)trifluoroacetamide is C8H18F3NOSi2.
What is the molecular weight of N,N-Bis(trimethylsilyl)trifluoroacetamide?
The molecular weight of N,N-Bis(trimethylsilyl)trifluoroacetamide is 257.09 g/mol.
Where can I buy N,N-Bis(trimethylsilyl)trifluoroacetamide?
You can request a quote for N,N-Bis(trimethylsilyl)trifluoroacetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N,N-Bis(trimethylsilyl)trifluoroacetamide?
Yes, KEHONG BIO provides custom synthesis services for N,N-Bis(trimethylsilyl)trifluoroacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.