RefChem:283645
TL;DR: RefChem:283645 (CAS 21132-00-3) is a chemical compound with molecular formula C21H26ClN3O2 and molecular weight 387.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(diethylamino)acetyl]-3-(4-methylphenyl)-2H-quinazolin-4-one;hydrochloride
Also Known As: 4(1H)-Quinazolinone, 2,3-dihydro-1-(diethylaminoacetyl)-3-(p-tolyl)-, hydrochloride, 2,3-Dihydro-1-(diethylaminoacetyl)-3-(p-tolyl)-4(1H)-quinazolinone hydrochloride, 1-[2-(Diethylamino)acetyl]-3-(4-methylphenyl)-2H-quinazolin-4-onehydrochloride, 1-[2-(diethylamino)acetyl]-3-(4-methylphenyl)-2H-quinazolin-4-one hydrochloride, 1-[(Diethylamino)acetyl]-3-(4-methylphenyl)-2,3-dihydroquinazolin-4(1H)-one--hydrogen chloride (1/1)
| Molecular Formula | C21H26ClN3O2 |
|---|---|
| Molecular Weight | 387.17 g/mol |
| LogP | 3.71 |
| Topological Polar Surface Area | 43.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 387.17136 |
| Heavy Atoms | 27 |
| Complexity | 497.0 |
Chemical Identifiers
| CAS Number | 21132-00-3 |
|---|---|
| SMILES | CCN(CC)CC(=O)N1CN(C(=O)C2=CC=CC=C21)C3=CC=C(C=C3)C.Cl |
| InChIKey | HGEXMEJSSCGHSZ-UHFFFAOYSA-N |
Product Overview
RefChem:283645 (CAS 21132-00-3), with molecular formula C21H26ClN3O2 and molecular weight 387.17 g/mol. IUPAC: 1-[2-(diethylamino)acetyl]-3-(4-methylphenyl)-2H-quinazolin-4-one;hydrochloride.
Chemical Property Profile of RefChem:283645
Property Insights of RefChem:283645
The XLogP value of 3.71 indicates that RefChem:283645 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.9 Ų, RefChem:283645 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:283645 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:283645?
The CAS number of RefChem:283645 is 21132-00-3.
What is the molecular formula of RefChem:283645?
The molecular formula of RefChem:283645 is C21H26ClN3O2.
What is the molecular weight of RefChem:283645?
The molecular weight of RefChem:283645 is 387.17 g/mol.
Where can I buy RefChem:283645?
You can request a quote for RefChem:283645 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:283645?
Yes, KEHONG BIO provides custom synthesis services for RefChem:283645 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.