![8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 structure](/static/products/2110/21102-94-3.webp)
8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮
TL;DR: 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 (CAS 21102-94-3) is a chemical compound with molecular formula C22H31N3O3 and molecular weight 385.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮
8-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione
Also Known As: bmy-7378 free base, BMY 7378, GTPL9, Lopac-B-134, BMY 7378 dihydrochloride
| Molecular Formula | C22H31N3O3 |
|---|---|
| Molecular Weight | 385.24 g/mol |
| LogP | 2.8 |
| Topological Polar Surface Area | 53.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 385.23654 |
| Heavy Atoms | 28 |
| Complexity | 547.0 |
Chemical Identifiers
| CAS Number | 21102-94-3 |
|---|---|
| SMILES | COC1=CC=CC=C1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O |
| InChIKey | AYYCFGDXLUPJAQ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 (CAS 21102-94-3), with molecular formula C22H31N3O3 and molecular weight 385.24 g/mol. IUPAC: 8-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione.
Chemical Property Profile of 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮
Property Insights of 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮. With a topological polar surface area (TPSA) of 53.1 Ų, 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮?
The CAS number of 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 is 21102-94-3.
What is the molecular formula of 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮?
The molecular formula of 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 is C22H31N3O3.
What is the molecular weight of 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮?
The molecular weight of 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 is 385.24 g/mol.
Where can I buy 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮?
You can request a quote for 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮?
Yes, KEHONG BIO provides custom synthesis services for 8-{2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基}-8-氮杂螺[4.5]癸烷-7,9-二酮 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.