Orantinib structure

Orantinib

TL;DR: Orantinib (CAS 210644-62-5) is a chemical compound with molecular formula C18H18N2O3 and molecular weight 310.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid

Also Known As: Orantinib, Orantinibum, Orantinib [INN], TSU 68, SU 6668

CAS: 210644-62-5
Molecular Formula C18H18N2O3
Molecular Weight 310.13 g/mol
LogP 3.14144
Topological Polar Surface Area 82.19 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 2
Rotatable Bonds 4
Exact Mass 310.13174
Heavy Atoms 23
Complexity 830.7874

Chemical Identifiers

CAS Number 210644-62-5
SMILES CC1=C(NC(=C1CCC(=O)O)C)/C=C/2\C3=CC=CC=C3NC2=O

Product Overview

Orantinib (CAS 210644-62-5), with molecular formula C18H18N2O3 and molecular weight 310.13 g/mol. IUPAC: 3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Orantinib

XLogP
3.14144
TPSA (Topological Polar Surface Area)
82.19
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
2
Rotatable Bonds
4
Heavy Atoms
23
Complexity
830.7874
Exact Mass
310.13174
Monoisotopic Mass
310.13174
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Orantinib

The XLogP value of 3.14144 indicates that Orantinib is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 82.19 Ų falls within the moderate polarity range, balancing permeability and solubility for Orantinib. Following Lipinski's Rule of Five, Orantinib has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Orantinib?

The CAS number of Orantinib is 210644-62-5.

What is the molecular formula of Orantinib?

The molecular formula of Orantinib is C18H18N2O3.

What is the molecular weight of Orantinib?

The molecular weight of Orantinib is 310.13 g/mol.

Where can I buy Orantinib?

You can request a quote for Orantinib directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Orantinib?

Yes, KEHONG BIO provides custom synthesis services for Orantinib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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