8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one
TL;DR: 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one (CAS 21028-20-6) is a chemical compound with molecular formula C11H8F3NO2 and molecular weight 243.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-methoxy-2-(trifluoromethyl)-1H-quinolin-4-one
Also Known As: 4-Hydroxy-8-methoxy-2-(trifluoromethyl)quinoline, 8-Methoxy-2-(trifluoromethyl)-4-quinolinol, 8-methoxy-2-(trifluoromethyl)-1H-quinolin-4-one, 8-methoxy-2-(trifluoromethyl)quinolin-4-ol, methoxytrifluoromethylquinolinol
| Molecular Formula | C11H8F3NO2 |
|---|---|
| Molecular Weight | 243.05 g/mol |
| LogP | 2.4 |
| Topological Polar Surface Area | 38.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 243.05072 |
| Heavy Atoms | 17 |
| Complexity | 351.0 |
Chemical Identifiers
| CAS Number | 21028-20-6 |
|---|---|
| SMILES | COC1=CC=CC2=C1NC(=CC2=O)C(F)(F)F |
| InChIKey | PJTJOLUVQOIHEC-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one (CAS 21028-20-6), with molecular formula C11H8F3NO2 and molecular weight 243.05 g/mol. IUPAC: 8-methoxy-2-(trifluoromethyl)-1H-quinolin-4-one.
Chemical Property Profile of 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one
Property Insights of 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one. With a topological polar surface area (TPSA) of 38.3 Ų, 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one?
The CAS number of 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one is 21028-20-6.
What is the molecular formula of 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one?
The molecular formula of 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one is C11H8F3NO2.
What is the molecular weight of 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one?
The molecular weight of 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one is 243.05 g/mol.
Where can I buy 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one?
You can request a quote for 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 8-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.