7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one
TL;DR: 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one (CAS 209974-81-2) is a chemical compound with molecular formula C18H11NO3S and molecular weight 321.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-hydroxy-3-(2-phenyl-1,3-thiazol-4-yl)chromen-2-one
Also Known As: BAS 01020234, 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one, 7-hydroxy-3-(2-phenyl-1,3-thiazol-4-yl)chromen-2-one, 7-hydroxy-3-(2-phenylthiazol-4-yl)-2H-chromen-2-one, 2H-1-Benzopyran-2-one, 7-hydroxy-3-(2-phenyl-4-thiazolyl)-
| Molecular Formula | C18H11NO3S |
|---|---|
| Molecular Weight | 321.05 g/mol |
| LogP | 4.2891 |
| Topological Polar Surface Area | 63.33 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 321.04596 |
| Heavy Atoms | 23 |
| Complexity | 1050.7506 |
Chemical Identifiers
| CAS Number | 209974-81-2 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=NC(=CS2)C3=CC4=C(C=C(C=C4)O)OC3=O |
Product Overview
7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one (CAS 209974-81-2), with molecular formula C18H11NO3S and molecular weight 321.05 g/mol. IUPAC: 7-hydroxy-3-(2-phenyl-1,3-thiazol-4-yl)chromen-2-one.
Chemical Property Profile of 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one
Property Insights of 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one
The XLogP value of 4.2891 indicates that 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.33 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one. Following Lipinski's Rule of Five, 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one?
The CAS number of 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one is 209974-81-2.
What is the molecular formula of 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one?
The molecular formula of 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one is C18H11NO3S.
What is the molecular weight of 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one?
The molecular weight of 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one is 321.05 g/mol.
Where can I buy 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one?
You can request a quote for 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one?
Yes, KEHONG BIO provides custom synthesis services for 7-Hydroxy-3-(2-phenyl-thiazol-4-yl)-chromen-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.