RefChem:283647
TL;DR: RefChem:283647 (CAS 20887-29-0) is a chemical compound with molecular formula C19H22ClN3O3 and molecular weight 375.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(dimethylamino)acetyl]-3-(4-methoxyphenyl)-2H-quinazolin-4-one;hydrochloride
Also Known As: 4(1H)-Quinazolinone, 2,3-dihydro-1-(dimethylaminoacetyl)-3-(p-methoxyphenyl)-, hydrochloride, 2,3-Dihydro-1-(dimethylaminoacetyl)-3-(p-methoxyphenyl)-4(1H)-quinazolinone hydrochloride, 1-[2-(Dimethylamino)acetyl]-3-(4-methoxyphenyl)-2H-quinazolin-4-onehydrochloride, 1-[2-(dimethylamino)acetyl]-3-(4-methoxyphenyl)-2H-quinazolin-4-one hydrochloride, 1-[(Dimethylamino)acetyl]-3-(4-methoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one--hydrogen chloride (1/1)
| Molecular Formula | C19H22ClN3O3 |
|---|---|
| Molecular Weight | 375.13 g/mol |
| LogP | 2.63 |
| Topological Polar Surface Area | 53.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 375.13498 |
| Heavy Atoms | 26 |
| Complexity | 488.0 |
Chemical Identifiers
| CAS Number | 20887-29-0 |
|---|---|
| SMILES | CN(C)CC(=O)N1CN(C(=O)C2=CC=CC=C21)C3=CC=C(C=C3)OC.Cl |
| InChIKey | SACGUEKSGPQRSJ-UHFFFAOYSA-N |
Product Overview
RefChem:283647 (CAS 20887-29-0), with molecular formula C19H22ClN3O3 and molecular weight 375.13 g/mol. IUPAC: 1-[2-(dimethylamino)acetyl]-3-(4-methoxyphenyl)-2H-quinazolin-4-one;hydrochloride.
Chemical Property Profile of RefChem:283647
Property Insights of RefChem:283647
The XLogP value of 2.63 suggests moderate lipophilicity, balancing water solubility and membrane permeability for RefChem:283647. With a topological polar surface area (TPSA) of 53.1 Ų, RefChem:283647 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:283647 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:283647?
The CAS number of RefChem:283647 is 20887-29-0.
What is the molecular formula of RefChem:283647?
The molecular formula of RefChem:283647 is C19H22ClN3O3.
What is the molecular weight of RefChem:283647?
The molecular weight of RefChem:283647 is 375.13 g/mol.
Where can I buy RefChem:283647?
You can request a quote for RefChem:283647 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:283647?
Yes, KEHONG BIO provides custom synthesis services for RefChem:283647 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.