4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride
TL;DR: 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride (CAS 208108-75-2) is a chemical compound with molecular formula C12H6ClF3OS and molecular weight 289.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride
Also Known As: 4-phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride, 4-AMINO-5-CHLOROQUINOLINE, 4-phenyl-5-(trifluoromethyl)-2-thiophenecarbonyl chloride, 4-PHENYL-5- -2-THIOPHENECARBONYLCHLORIDE, 2-(Chlorocarbonyl)-4-phenyl-5-(trifluoromethyl)thiophene
| Molecular Formula | C12H6ClF3OS |
|---|---|
| Molecular Weight | 289.98 g/mol |
| LogP | 4.8129 |
| Topological Polar Surface Area | 17.07 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 289.978 |
| Heavy Atoms | 18 |
| Complexity | 574.7536 |
Chemical Identifiers
| CAS Number | 208108-75-2 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=C(SC(=C2)C(=O)Cl)C(F)(F)F |
Product Overview
4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride (CAS 208108-75-2), with molecular formula C12H6ClF3OS and molecular weight 289.98 g/mol. IUPAC: 4-phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride.
Chemical Property Profile of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride
Property Insights of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride
The XLogP value of 4.8129 indicates that 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.07 Ų, 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride?
The CAS number of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride is 208108-75-2.
What is the molecular formula of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride?
The molecular formula of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride is C12H6ClF3OS.
What is the molecular weight of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride?
The molecular weight of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride is 289.98 g/mol.
Where can I buy 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride?
You can request a quote for 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride?
Yes, KEHONG BIO provides custom synthesis services for 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.