5-TRITC structure

5-TRITC

TL;DR: 5-TRITC (CAS 20746-54-7) is a chemical compound with molecular formula C25H21N3O3S and molecular weight 443.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3',6'-bis(dimethylamino)-6-isothiocyanatospiro[2-benzofuran-3,9'-xanthene]-1-one

Also Known As: TRITC, Tetramethylrhodamine-5-isothiocyanate, Tetramethylrhodamine isothiocyanate mixed isomers, Fluoran, 3',6'-bis(dimethylamino)-5-isothiocyanato-, Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-bis(dimethylamino)-5-isothiocyanato-

CAS: 20746-54-7
Molecular Formula C25H21N3O3S
Molecular Weight 443.13 g/mol
LogP 5.8
Topological Polar Surface Area 86.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 7
Rotatable Bonds 3
Exact Mass 443.13037
Heavy Atoms 32
Complexity 750.0

Chemical Identifiers

CAS Number 20746-54-7
SMILES CN(C)C1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)N=C=S)C(=O)O3)C5=C(O2)C=C(C=C5)N(C)C
InChIKey GKMSREGJMYNJMR-UHFFFAOYSA-N

Product Overview

5-TRITC (CAS 20746-54-7), with molecular formula C25H21N3O3S and molecular weight 443.13 g/mol. IUPAC: 3',6'-bis(dimethylamino)-6-isothiocyanatospiro[2-benzofuran-3,9'-xanthene]-1-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 5-TRITC

XLogP
5.8
TPSA (Topological Polar Surface Area)
86.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
7
Rotatable Bonds
3
Heavy Atoms
32
Complexity
750.0
Exact Mass
443.13037
Monoisotopic Mass
443.13037
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5-TRITC

The XLogP value of 5.8 indicates that 5-TRITC is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-TRITC. Following Lipinski's Rule of Five, 5-TRITC has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5-TRITC?

The CAS number of 5-TRITC is 20746-54-7.

What is the molecular formula of 5-TRITC?

The molecular formula of 5-TRITC is C25H21N3O3S.

What is the molecular weight of 5-TRITC?

The molecular weight of 5-TRITC is 443.13 g/mol.

Where can I buy 5-TRITC?

You can request a quote for 5-TRITC directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5-TRITC?

Yes, KEHONG BIO provides custom synthesis services for 5-TRITC and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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