Tenofovir diphosphate
TL;DR: Tenofovir diphosphate (CAS 206646-04-0) is a chemical compound with molecular formula C9H16N5O10P3 and molecular weight 447.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid
Also Known As: tenofovir diphosphate, PMPApp, TenofovirDiphosphate, Tenofovir-DP, PMPA diphosphate
| Molecular Formula | C9H16N5O10P3 |
|---|---|
| Molecular Weight | 447.01 g/mol |
| LogP | 0.1828 |
| Topological Polar Surface Area | 229.44 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 9 |
| Exact Mass | 447.01102 |
| Heavy Atoms | 27 |
| Complexity | 958.93024 |
Chemical Identifiers
| CAS Number | 206646-04-0 |
|---|---|
| SMILES | C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(O)OP(=O)(O)OP(=O)(O)O |
Product Overview
Tenofovir diphosphate (CAS 206646-04-0), with molecular formula C9H16N5O10P3 and molecular weight 447.01 g/mol. IUPAC: [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid.
Chemical Property Profile of Tenofovir diphosphate
Property Insights of Tenofovir diphosphate
The XLogP value of 0.1828 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tenofovir diphosphate. The TPSA of 229.44 Ų indicates high polarity, suggesting Tenofovir diphosphate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tenofovir diphosphate has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tenofovir diphosphate?
The CAS number of Tenofovir diphosphate is 206646-04-0.
What is the molecular formula of Tenofovir diphosphate?
The molecular formula of Tenofovir diphosphate is C9H16N5O10P3.
What is the molecular weight of Tenofovir diphosphate?
The molecular weight of Tenofovir diphosphate is 447.01 g/mol.
Where can I buy Tenofovir diphosphate?
You can request a quote for Tenofovir diphosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tenofovir diphosphate?
Yes, KEHONG BIO provides custom synthesis services for Tenofovir diphosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.