(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride
TL;DR: (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride (CAS 20445-33-4) is a chemical compound with molecular formula C10H8ClF3O2 and molecular weight 252.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
Also Known As: Mosher's acid chloride, (R)-(-)-MTPA-Cl, R-MTPA-Cl, (-)-Mosher's Acid Chloride, (-)-MTPA-Cl
| Molecular Formula | C10H8ClF3O2 |
|---|---|
| Molecular Weight | 252.02 g/mol |
| LogP | 2.856 |
| Topological Polar Surface Area | 26.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 252.0165 |
| Heavy Atoms | 16 |
| Complexity | 377.40057 |
Chemical Identifiers
| CAS Number | 20445-33-4 |
|---|---|
| SMILES | CO[C@@](C1=CC=CC=C1)(C(=O)Cl)C(F)(F)F |
Product Overview
(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride (CAS 20445-33-4), with molecular formula C10H8ClF3O2 and molecular weight 252.02 g/mol. IUPAC: (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride.
Chemical Property Profile of (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride
Property Insights of (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride
The XLogP value of 2.856 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride. With a topological polar surface area (TPSA) of 26.3 Ų, (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride?
The CAS number of (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride is 20445-33-4.
What is the molecular formula of (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride?
The molecular formula of (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride is C10H8ClF3O2.
What is the molecular weight of (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride?
The molecular weight of (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride is 252.02 g/mol.
Where can I buy (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride?
You can request a quote for (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride?
Yes, KEHONG BIO provides custom synthesis services for (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.