Semaxinib
TL;DR: Semaxinib (CAS 204005-46-9) is a chemical compound with molecular formula C15H14N2O and molecular weight 238.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
Also Known As: Semaxanib, Semaxinib, emaxanib, Romiplostim, Z-Semaxanib
| Molecular Formula | C15H14N2O |
|---|---|
| Molecular Weight | 238.11 g/mol |
| LogP | 2.5 |
| Topological Polar Surface Area | 44.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 238.11061 |
| Heavy Atoms | 18 |
| Complexity | 377.0 |
Chemical Identifiers
| CAS Number | 204005-46-9 |
|---|---|
| SMILES | CC1=CC(=C(N1)C=C2C3=CC=CC=C3NC2=O)C |
| InChIKey | WUWDLXZGHZSWQZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Semaxinib (CAS 204005-46-9), with molecular formula C15H14N2O and molecular weight 238.11 g/mol. IUPAC: 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one.
Chemical Property Profile of Semaxinib
Property Insights of Semaxinib
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Semaxinib. With a topological polar surface area (TPSA) of 44.9 Ų, Semaxinib exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Semaxinib has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Semaxinib?
The CAS number of Semaxinib is 204005-46-9.
What is the molecular formula of Semaxinib?
The molecular formula of Semaxinib is C15H14N2O.
What is the molecular weight of Semaxinib?
The molecular weight of Semaxinib is 238.11 g/mol.
Where can I buy Semaxinib?
You can request a quote for Semaxinib directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Semaxinib?
Yes, KEHONG BIO provides custom synthesis services for Semaxinib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.